Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

The consequences of microglial activation in the aging human brain remain unknown. This study quantified microglial morphology and density in the elderly human brain to show that cortical microglial activation strongly associates with AD pathogenesis and may be an upstream contributor to cognitive d...

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Auteurs principaux: Daniel Felsky, Tina Roostaei, Kwangsik Nho, Shannon L. Risacher, Elizabeth M. Bradshaw, Vlad Petyuk, Julie A. Schneider, Andrew Saykin, David A. Bennett, Philip L. De Jager
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/5c2b0cd3de2c44ac9e972835b9851021
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