CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation

RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V...

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Autores principales: Somsakul Pop Wongpalee, Shiheng Liu, Javier Gallego-Bartolomé, Alexander Leitner, Ruedi Aebersold, Wanlu Liu, Linda Yen, Maria A. Nohales, Peggy Hsuanyu Kuo, Ajay A. Vashisht, James A. Wohlschlegel, Suhua Feng, Steve A. Kay, Z. Hong Zhou, Steven E. Jacobsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5c382745983c4f368ca62e85724d1bdc
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Sumario:RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V recruitment.