CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation

RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V...

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Autores principales: Somsakul Pop Wongpalee, Shiheng Liu, Javier Gallego-Bartolomé, Alexander Leitner, Ruedi Aebersold, Wanlu Liu, Linda Yen, Maria A. Nohales, Peggy Hsuanyu Kuo, Ajay A. Vashisht, James A. Wohlschlegel, Suhua Feng, Steve A. Kay, Z. Hong Zhou, Steven E. Jacobsen
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5c382745983c4f368ca62e85724d1bdc
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spelling oai:doaj.org-article:5c382745983c4f368ca62e85724d1bdc2021-12-02T15:35:55ZCryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation10.1038/s41467-019-11759-92041-1723https://doaj.org/article/5c382745983c4f368ca62e85724d1bdc2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11759-9https://doaj.org/toc/2041-1723RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V recruitment.Somsakul Pop WongpaleeShiheng LiuJavier Gallego-BartoloméAlexander LeitnerRuedi AebersoldWanlu LiuLinda YenMaria A. NohalesPeggy Hsuanyu KuoAjay A. VashishtJames A. WohlschlegelSuhua FengSteve A. KayZ. Hong ZhouSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Somsakul Pop Wongpalee
Shiheng Liu
Javier Gallego-Bartolomé
Alexander Leitner
Ruedi Aebersold
Wanlu Liu
Linda Yen
Maria A. Nohales
Peggy Hsuanyu Kuo
Ajay A. Vashisht
James A. Wohlschlegel
Suhua Feng
Steve A. Kay
Z. Hong Zhou
Steven E. Jacobsen
CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
description RNA polymerase V transcription in plants, which is needed DNA methylation and transcriptional silencing, requires components of the DDR complex. Here the authors show that all components of the DDR complex co-localize with Pol V and report the cryoEM structures of two complexes associated with Pol V recruitment.
format article
author Somsakul Pop Wongpalee
Shiheng Liu
Javier Gallego-Bartolomé
Alexander Leitner
Ruedi Aebersold
Wanlu Liu
Linda Yen
Maria A. Nohales
Peggy Hsuanyu Kuo
Ajay A. Vashisht
James A. Wohlschlegel
Suhua Feng
Steve A. Kay
Z. Hong Zhou
Steven E. Jacobsen
author_facet Somsakul Pop Wongpalee
Shiheng Liu
Javier Gallego-Bartolomé
Alexander Leitner
Ruedi Aebersold
Wanlu Liu
Linda Yen
Maria A. Nohales
Peggy Hsuanyu Kuo
Ajay A. Vashisht
James A. Wohlschlegel
Suhua Feng
Steve A. Kay
Z. Hong Zhou
Steven E. Jacobsen
author_sort Somsakul Pop Wongpalee
title CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
title_short CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
title_full CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
title_fullStr CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
title_full_unstemmed CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
title_sort cryoem structures of arabidopsis ddr complexes involved in rna-directed dna methylation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/5c382745983c4f368ca62e85724d1bdc
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