Microbial metabolite sensor GPR43 controls severity of experimental GVHD

The microbial metabolite sensor GPR43 has been previously shown to be a crucial modulator of immune responses. Here the authors show GPR43 is required for controlling disease pathology severity in the context of experimental models of GVHD.

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Autores principales:	Hideaki Fujiwara, Melissa D. Docampo, Mary Riwes, Daniel Peltier, Tomomi Toubai, Israel Henig, S. Julia Wu, Stephanie Kim, Austin Taylor, Stuart Brabbs, Chen Liu, Cynthia Zajac, Katherine Oravecz-Wilson, Yaping Sun, Gabriel Núñez, John E. Levine, Marcel R.M. van den Brink, James L. M. Ferrara, Pavan Reddy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5c3db952590146dbaba8c347ece59caa
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spelling	oai:doaj.org-article:5c3db952590146dbaba8c347ece59caa2021-12-02T14:38:52ZMicrobial metabolite sensor GPR43 controls severity of experimental GVHD10.1038/s41467-018-06048-w2041-1723https://doaj.org/article/5c3db952590146dbaba8c347ece59caa2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06048-whttps://doaj.org/toc/2041-1723The microbial metabolite sensor GPR43 has been previously shown to be a crucial modulator of immune responses. Here the authors show GPR43 is required for controlling disease pathology severity in the context of experimental models of GVHD.Hideaki FujiwaraMelissa D. DocampoMary RiwesDaniel PeltierTomomi ToubaiIsrael HenigS. Julia WuStephanie KimAustin TaylorStuart BrabbsChen LiuCynthia ZajacKatherine Oravecz-WilsonYaping SunGabriel NúñezJohn E. LevineMarcel R.M. van den BrinkJames L. M. FerraraPavan ReddyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hideaki Fujiwara Melissa D. Docampo Mary Riwes Daniel Peltier Tomomi Toubai Israel Henig S. Julia Wu Stephanie Kim Austin Taylor Stuart Brabbs Chen Liu Cynthia Zajac Katherine Oravecz-Wilson Yaping Sun Gabriel Núñez John E. Levine Marcel R.M. van den Brink James L. M. Ferrara Pavan Reddy Microbial metabolite sensor GPR43 controls severity of experimental GVHD
description	The microbial metabolite sensor GPR43 has been previously shown to be a crucial modulator of immune responses. Here the authors show GPR43 is required for controlling disease pathology severity in the context of experimental models of GVHD.
format	article
author	Hideaki Fujiwara Melissa D. Docampo Mary Riwes Daniel Peltier Tomomi Toubai Israel Henig S. Julia Wu Stephanie Kim Austin Taylor Stuart Brabbs Chen Liu Cynthia Zajac Katherine Oravecz-Wilson Yaping Sun Gabriel Núñez John E. Levine Marcel R.M. van den Brink James L. M. Ferrara Pavan Reddy
author_facet	Hideaki Fujiwara Melissa D. Docampo Mary Riwes Daniel Peltier Tomomi Toubai Israel Henig S. Julia Wu Stephanie Kim Austin Taylor Stuart Brabbs Chen Liu Cynthia Zajac Katherine Oravecz-Wilson Yaping Sun Gabriel Núñez John E. Levine Marcel R.M. van den Brink James L. M. Ferrara Pavan Reddy
author_sort	Hideaki Fujiwara
title	Microbial metabolite sensor GPR43 controls severity of experimental GVHD
title_short	Microbial metabolite sensor GPR43 controls severity of experimental GVHD
title_full	Microbial metabolite sensor GPR43 controls severity of experimental GVHD
title_fullStr	Microbial metabolite sensor GPR43 controls severity of experimental GVHD
title_full_unstemmed	Microbial metabolite sensor GPR43 controls severity of experimental GVHD
title_sort	microbial metabolite sensor gpr43 controls severity of experimental gvhd
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5c3db952590146dbaba8c347ece59caa
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Microbial metabolite sensor GPR43 controls severity of experimental GVHD

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