Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis

Ebola virus (EBOV) VP30 is a multifunctional protein that plays a role in transcription, but molecular details remain unknown. Here, using X-ray crystallography and minigenome assays, Xuet al. define the interaction between VP30 and a portion of NP that is critical for optimal EBOV RNA synthesis.

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Autores principales: Wei Xu, Priya Luthra, Chao Wu, Jyoti Batra, Daisy W. Leung, Christopher F. Basler, Gaya K. Amarasinghe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/5c4091a760484f9a90a55306fceabb20
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