Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue

Enhancing thermogenesis is a promising therapeutic strategy for promoting metabolic health. Here the authors show that adipocyte-secreted BMP8b contributes to optimizing the thermogenic response by remodeling of the neuro-vascular networks in brown and white adipose tissue.

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Autores principales: Vanessa Pellegrinelli, Vivian J. Peirce, Laura Howard, Samuel Virtue, Dénes Türei, Martina Senzacqua, Andrea Frontini, Jeffrey W. Dalley, Antony R. Horton, Guillaume Bidault, Ilenia Severi, Andrew Whittle, Kamal Rahmouni, Julio Saez-Rodriguez, Saverio Cinti, Alun M. Davies, Antonio Vidal-Puig
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5c42b2a14fae4857a4e5850a489dadfe
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spelling oai:doaj.org-article:5c42b2a14fae4857a4e5850a489dadfe2021-12-02T17:32:29ZAdipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue10.1038/s41467-018-07453-x2041-1723https://doaj.org/article/5c42b2a14fae4857a4e5850a489dadfe2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07453-xhttps://doaj.org/toc/2041-1723Enhancing thermogenesis is a promising therapeutic strategy for promoting metabolic health. Here the authors show that adipocyte-secreted BMP8b contributes to optimizing the thermogenic response by remodeling of the neuro-vascular networks in brown and white adipose tissue.Vanessa PellegrinelliVivian J. PeirceLaura HowardSamuel VirtueDénes TüreiMartina SenzacquaAndrea FrontiniJeffrey W. DalleyAntony R. HortonGuillaume BidaultIlenia SeveriAndrew WhittleKamal RahmouniJulio Saez-RodriguezSaverio CintiAlun M. DaviesAntonio Vidal-PuigNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vanessa Pellegrinelli
Vivian J. Peirce
Laura Howard
Samuel Virtue
Dénes Türei
Martina Senzacqua
Andrea Frontini
Jeffrey W. Dalley
Antony R. Horton
Guillaume Bidault
Ilenia Severi
Andrew Whittle
Kamal Rahmouni
Julio Saez-Rodriguez
Saverio Cinti
Alun M. Davies
Antonio Vidal-Puig
Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
description Enhancing thermogenesis is a promising therapeutic strategy for promoting metabolic health. Here the authors show that adipocyte-secreted BMP8b contributes to optimizing the thermogenic response by remodeling of the neuro-vascular networks in brown and white adipose tissue.
format article
author Vanessa Pellegrinelli
Vivian J. Peirce
Laura Howard
Samuel Virtue
Dénes Türei
Martina Senzacqua
Andrea Frontini
Jeffrey W. Dalley
Antony R. Horton
Guillaume Bidault
Ilenia Severi
Andrew Whittle
Kamal Rahmouni
Julio Saez-Rodriguez
Saverio Cinti
Alun M. Davies
Antonio Vidal-Puig
author_facet Vanessa Pellegrinelli
Vivian J. Peirce
Laura Howard
Samuel Virtue
Dénes Türei
Martina Senzacqua
Andrea Frontini
Jeffrey W. Dalley
Antony R. Horton
Guillaume Bidault
Ilenia Severi
Andrew Whittle
Kamal Rahmouni
Julio Saez-Rodriguez
Saverio Cinti
Alun M. Davies
Antonio Vidal-Puig
author_sort Vanessa Pellegrinelli
title Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
title_short Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
title_full Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
title_fullStr Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
title_full_unstemmed Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
title_sort adipocyte-secreted bmp8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5c42b2a14fae4857a4e5850a489dadfe
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