An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum

O’Keefe et al. investigate the integration of type III single-pass transmembrane proteins targeted to the ER and examine the roles of the ER membrane complex, Sec61 complex and signal recognition particle receptor. As a result, the authors propose an alternative mechanism of insertion, reconciling t...

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Autores principales:	Sarah O’Keefe, Guanghui Zong, Kwabena B. Duah, Lauren E. Andrews, Wei Q. Shi, Stephen High
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5c449021283a45d288dc2d9c2bd63056
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spelling	oai:doaj.org-article:5c449021283a45d288dc2d9c2bd630562021-12-02T14:34:01ZAn alternative pathway for membrane protein biogenesis at the endoplasmic reticulum10.1038/s42003-021-02363-z2399-3642https://doaj.org/article/5c449021283a45d288dc2d9c2bd630562021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02363-zhttps://doaj.org/toc/2399-3642O’Keefe et al. investigate the integration of type III single-pass transmembrane proteins targeted to the ER and examine the roles of the ER membrane complex, Sec61 complex and signal recognition particle receptor. As a result, the authors propose an alternative mechanism of insertion, reconciling the ability of type III transmembrane proteins to bypass an ipomoeassin-F-mediated blockade of membrane integration.Sarah O’KeefeGuanghui ZongKwabena B. DuahLauren E. AndrewsWei Q. ShiStephen HighNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Sarah O’Keefe Guanghui Zong Kwabena B. Duah Lauren E. Andrews Wei Q. Shi Stephen High An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
description	O’Keefe et al. investigate the integration of type III single-pass transmembrane proteins targeted to the ER and examine the roles of the ER membrane complex, Sec61 complex and signal recognition particle receptor. As a result, the authors propose an alternative mechanism of insertion, reconciling the ability of type III transmembrane proteins to bypass an ipomoeassin-F-mediated blockade of membrane integration.
format	article
author	Sarah O’Keefe Guanghui Zong Kwabena B. Duah Lauren E. Andrews Wei Q. Shi Stephen High
author_facet	Sarah O’Keefe Guanghui Zong Kwabena B. Duah Lauren E. Andrews Wei Q. Shi Stephen High
author_sort	Sarah O’Keefe
title	An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
title_short	An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
title_full	An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
title_fullStr	An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
title_full_unstemmed	An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
title_sort	alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5c449021283a45d288dc2d9c2bd63056
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An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum

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