NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH

Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated substances from venons, with one or more specific actions on victims. Many of these compounds have action o...

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Autores principales: Jaime A. PEREAÑEZ, Leidy J. VARGAS
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Publicado: Universidad de Antioquia 2009
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Acceso en línea:https://doaj.org/article/5c44fd8b4481443bb96d106fd9f8c5e1
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spelling oai:doaj.org-article:5c44fd8b4481443bb96d106fd9f8c5e12021-11-19T04:16:00ZNEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH0121-40042145-2660https://doaj.org/article/5c44fd8b4481443bb96d106fd9f8c5e12009-05-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/1437https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated substances from venons, with one or more specific actions on victims. Many of these compounds have action on specific receptors located on the central and/or peripheral nervous system, while others exert their effects by acting on other proteins. Since the discovery in 1971 of the peptide that gave rise to Captopril and the fact that a lot of toxins are useful as tools for physiological process studies, animal venoms began to be watched as sources rich in bioactive compounds and its potential use as therapeutic agents is now considered. There are now different drugs and diagnostic or basic investigation tools derivated from toxins. This review based on publications from the last 10 years pretends to provide a current view of the use of some of these molecules as tools in different fields of biomedicine and pharmacy, and in the application of these as new alternative therapeutic agents or as models in designing them. Jaime A. PEREAÑEZLeidy J. VARGASUniversidad de Antioquiaarticlevenomneurotoxinreceptortherapeutic agentsFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 1 (2009)
institution DOAJ
collection DOAJ
language EN
topic venom
neurotoxin
receptor
therapeutic agents
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
spellingShingle venom
neurotoxin
receptor
therapeutic agents
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
Jaime A. PEREAÑEZ
Leidy J. VARGAS
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
description Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated substances from venons, with one or more specific actions on victims. Many of these compounds have action on specific receptors located on the central and/or peripheral nervous system, while others exert their effects by acting on other proteins. Since the discovery in 1971 of the peptide that gave rise to Captopril and the fact that a lot of toxins are useful as tools for physiological process studies, animal venoms began to be watched as sources rich in bioactive compounds and its potential use as therapeutic agents is now considered. There are now different drugs and diagnostic or basic investigation tools derivated from toxins. This review based on publications from the last 10 years pretends to provide a current view of the use of some of these molecules as tools in different fields of biomedicine and pharmacy, and in the application of these as new alternative therapeutic agents or as models in designing them.
format article
author Jaime A. PEREAÑEZ
Leidy J. VARGAS
author_facet Jaime A. PEREAÑEZ
Leidy J. VARGAS
author_sort Jaime A. PEREAÑEZ
title NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
title_short NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
title_full NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
title_fullStr NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
title_full_unstemmed NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
title_sort neurotoxins from invertebrates as alternative therapeutic agents and tools in basic research
publisher Universidad de Antioquia
publishDate 2009
url https://doaj.org/article/5c44fd8b4481443bb96d106fd9f8c5e1
work_keys_str_mv AT jaimeapereanez neurotoxinsfrominvertebratesasalternativetherapeuticagentsandtoolsinbasicresearch
AT leidyjvargas neurotoxinsfrominvertebratesasalternativetherapeuticagentsandtoolsinbasicresearch
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