NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH
Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated substances from venons, with one or more specific actions on victims. Many of these compounds have action o...
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Universidad de Antioquia
2009
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oai:doaj.org-article:5c44fd8b4481443bb96d106fd9f8c5e12021-11-19T04:16:00ZNEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH0121-40042145-2660https://doaj.org/article/5c44fd8b4481443bb96d106fd9f8c5e12009-05-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/1437https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated substances from venons, with one or more specific actions on victims. Many of these compounds have action on specific receptors located on the central and/or peripheral nervous system, while others exert their effects by acting on other proteins. Since the discovery in 1971 of the peptide that gave rise to Captopril and the fact that a lot of toxins are useful as tools for physiological process studies, animal venoms began to be watched as sources rich in bioactive compounds and its potential use as therapeutic agents is now considered. There are now different drugs and diagnostic or basic investigation tools derivated from toxins. This review based on publications from the last 10 years pretends to provide a current view of the use of some of these molecules as tools in different fields of biomedicine and pharmacy, and in the application of these as new alternative therapeutic agents or as models in designing them. Jaime A. PEREAÑEZLeidy J. VARGASUniversidad de Antioquiaarticlevenomneurotoxinreceptortherapeutic agentsFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 1 (2009) |
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venom neurotoxin receptor therapeutic agents Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 |
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venom neurotoxin receptor therapeutic agents Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Jaime A. PEREAÑEZ Leidy J. VARGAS NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
description |
Animal venoms are a complex mixture of proteins, peptides, enzymes and trace elements such as
carbohydrates and salts, which aim to immobilize the prey and begin digestion. Toxins are isolated
substances from venons, with one or more specific actions on victims. Many of these compounds have
action on specific receptors located on the central and/or peripheral nervous system, while others exert their
effects by acting on other proteins. Since the discovery in 1971 of the peptide that gave rise to Captopril
and the fact that a lot of toxins are useful as tools for physiological process studies, animal venoms began
to be watched as sources rich in bioactive compounds and its potential use as therapeutic agents is now
considered. There are now different drugs and diagnostic or basic investigation tools derivated from
toxins. This review based on publications from the last 10 years pretends to provide a current view of
the use of some of these molecules as tools in different fields of biomedicine and pharmacy, and in the
application of these as new alternative therapeutic agents or as models in designing them.
|
format |
article |
author |
Jaime A. PEREAÑEZ Leidy J. VARGAS |
author_facet |
Jaime A. PEREAÑEZ Leidy J. VARGAS |
author_sort |
Jaime A. PEREAÑEZ |
title |
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
title_short |
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
title_full |
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
title_fullStr |
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
title_full_unstemmed |
NEUROTOXINS FROM INVERTEBRATES AS ALTERNATIVE THERAPEUTIC AGENTS AND TOOLS IN BASIC RESEARCH |
title_sort |
neurotoxins from invertebrates as alternative therapeutic agents and tools in basic research |
publisher |
Universidad de Antioquia |
publishDate |
2009 |
url |
https://doaj.org/article/5c44fd8b4481443bb96d106fd9f8c5e1 |
work_keys_str_mv |
AT jaimeapereanez neurotoxinsfrominvertebratesasalternativetherapeuticagentsandtoolsinbasicresearch AT leidyjvargas neurotoxinsfrominvertebratesasalternativetherapeuticagentsandtoolsinbasicresearch |
_version_ |
1718420457658515456 |