Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade.

<h4>Background</h4>Antidepressant drugs (ADs) have been shown to activate BDNF (brain-derived neurotrophic factor) receptor TrkB in the rodent brain but the mechanism underlying this phenomenon remains unclear. ADs act as monoamine reuptake inhibitors and after prolonged treatments regul...

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Bibliographic Details
Main Authors: Tomi Rantamäki, Liisa Vesa, Hanna Antila, Antonio Di Lieto, Päivi Tammela, Angelika Schmitt, Klaus-Peter Lesch, Maribel Rios, Eero Castrén
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/5c6103360c4f4187b09e9cb64ab52681
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