Toll-like receptor 4 deficiency accelerates the development of insulin-deficient diabetes in non-obese diabetic mice.

<h4>Background/objective</h4>Toll-like receptors (TLR) mediate the recognition of microbial constituents and stress-induced endogenous ligands by the immune system. They may also be involved in the maintenance or break down of tolerance against autologous antigens. The aim of our investi...

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Auteurs principaux: Elke Gülden, Masaru Ihira, Atsushi Ohashi, Anna Lena Reinbeck, Marina A Freudenberg, Hubert Kolb, Volker Burkart
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
Q
Accès en ligne:https://doaj.org/article/5c6aea1a33e14d68962e75adc416e65c
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