The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis

Tubulogenesis is required for the formation of many internal structures including the trachea. Here, the authors show that the potassium channel KCNJ13 regulates tracheal tube formation, with shorter tracheas forming in mutant mice due in part to changes in actin organization in tracheal smooth musc...

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Autores principales:	Wenguang Yin, Hyun-Taek Kim, ShengPeng Wang, Felix Gunawan, Lei Wang, Keishi Kishimoto, Hua Zhong, Dany Roman, Jens Preussner, Stefan Guenther, Viola Graef, Carmen Buettner, Beate Grohmann, Mario Looso, Mitsuru Morimoto, Graeme Mardon, Stefan Offermanns, Didier Y. R. Stainier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5c7dc446a7fa45a0a6142c125ca9449f
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spelling	oai:doaj.org-article:5c7dc446a7fa45a0a6142c125ca9449f2021-12-02T17:31:14ZThe potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis10.1038/s41467-018-05043-52041-1723https://doaj.org/article/5c7dc446a7fa45a0a6142c125ca9449f2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05043-5https://doaj.org/toc/2041-1723Tubulogenesis is required for the formation of many internal structures including the trachea. Here, the authors show that the potassium channel KCNJ13 regulates tracheal tube formation, with shorter tracheas forming in mutant mice due in part to changes in actin organization in tracheal smooth muscle cells.Wenguang YinHyun-Taek KimShengPeng WangFelix GunawanLei WangKeishi KishimotoHua ZhongDany RomanJens PreussnerStefan GuentherViola GraefCarmen BuettnerBeate GrohmannMario LoosoMitsuru MorimotoGraeme MardonStefan OffermannsDidier Y. R. StainierNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenguang Yin Hyun-Taek Kim ShengPeng Wang Felix Gunawan Lei Wang Keishi Kishimoto Hua Zhong Dany Roman Jens Preussner Stefan Guenther Viola Graef Carmen Buettner Beate Grohmann Mario Looso Mitsuru Morimoto Graeme Mardon Stefan Offermanns Didier Y. R. Stainier The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
description	Tubulogenesis is required for the formation of many internal structures including the trachea. Here, the authors show that the potassium channel KCNJ13 regulates tracheal tube formation, with shorter tracheas forming in mutant mice due in part to changes in actin organization in tracheal smooth muscle cells.
format	article
author	Wenguang Yin Hyun-Taek Kim ShengPeng Wang Felix Gunawan Lei Wang Keishi Kishimoto Hua Zhong Dany Roman Jens Preussner Stefan Guenther Viola Graef Carmen Buettner Beate Grohmann Mario Looso Mitsuru Morimoto Graeme Mardon Stefan Offermanns Didier Y. R. Stainier
author_facet	Wenguang Yin Hyun-Taek Kim ShengPeng Wang Felix Gunawan Lei Wang Keishi Kishimoto Hua Zhong Dany Roman Jens Preussner Stefan Guenther Viola Graef Carmen Buettner Beate Grohmann Mario Looso Mitsuru Morimoto Graeme Mardon Stefan Offermanns Didier Y. R. Stainier
author_sort	Wenguang Yin
title	The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
title_short	The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
title_full	The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
title_fullStr	The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
title_full_unstemmed	The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
title_sort	potassium channel kcnj13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5c7dc446a7fa45a0a6142c125ca9449f
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The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis

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