A method for measuring the distribution of the shortest telomeres in cells and tissues

Short telomeres are a hallmark of senescence and can result in genomic instability as well as cancer progression. Here, the authors present TeSLA, a technique to accurately detect telomeres under 1 kb in length.

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Autores principales:	Tsung-Po Lai, Ning Zhang, Jungsik Noh, Ilgen Mender, Enzo Tedone, Ejun Huang, Woodring E. Wright, Gaudenz Danuser, Jerry W. Shay
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5c7e184272eb490ebbc0a34207c6f69d
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spelling	oai:doaj.org-article:5c7e184272eb490ebbc0a34207c6f69d2021-12-02T14:42:27ZA method for measuring the distribution of the shortest telomeres in cells and tissues10.1038/s41467-017-01291-z2041-1723https://doaj.org/article/5c7e184272eb490ebbc0a34207c6f69d2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01291-zhttps://doaj.org/toc/2041-1723Short telomeres are a hallmark of senescence and can result in genomic instability as well as cancer progression. Here, the authors present TeSLA, a technique to accurately detect telomeres under 1 kb in length.Tsung-Po LaiNing ZhangJungsik NohIlgen MenderEnzo TedoneEjun HuangWoodring E. WrightGaudenz DanuserJerry W. ShayNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tsung-Po Lai Ning Zhang Jungsik Noh Ilgen Mender Enzo Tedone Ejun Huang Woodring E. Wright Gaudenz Danuser Jerry W. Shay A method for measuring the distribution of the shortest telomeres in cells and tissues
description	Short telomeres are a hallmark of senescence and can result in genomic instability as well as cancer progression. Here, the authors present TeSLA, a technique to accurately detect telomeres under 1 kb in length.
format	article
author	Tsung-Po Lai Ning Zhang Jungsik Noh Ilgen Mender Enzo Tedone Ejun Huang Woodring E. Wright Gaudenz Danuser Jerry W. Shay
author_facet	Tsung-Po Lai Ning Zhang Jungsik Noh Ilgen Mender Enzo Tedone Ejun Huang Woodring E. Wright Gaudenz Danuser Jerry W. Shay
author_sort	Tsung-Po Lai
title	A method for measuring the distribution of the shortest telomeres in cells and tissues
title_short	A method for measuring the distribution of the shortest telomeres in cells and tissues
title_full	A method for measuring the distribution of the shortest telomeres in cells and tissues
title_fullStr	A method for measuring the distribution of the shortest telomeres in cells and tissues
title_full_unstemmed	A method for measuring the distribution of the shortest telomeres in cells and tissues
title_sort	method for measuring the distribution of the shortest telomeres in cells and tissues
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5c7e184272eb490ebbc0a34207c6f69d
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A method for measuring the distribution of the shortest telomeres in cells and tissues

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