Prognosis and risk factors of ERCP pancreatitis in elderly

Abstract Post Endoscopic Retrograde Cholangiopancreatography (ERCP) pancreatitis is one of the most serious complications of ERCP. Our study aims to investigate the risk, predisposing factors and prognosis of pancreatitis after ERCP in elderly patients. Patients referred to the ERCP unit between Apr...

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Autores principales:	Erhan Ergin, Nevin Oruç, Galip Ersöz, Oktay Tekeşin, Ömer Özütemiz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5c83d0f2fcab4ce88729b9499cf7e536
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spelling	oai:doaj.org-article:5c83d0f2fcab4ce88729b9499cf7e5362021-12-02T14:53:49ZPrognosis and risk factors of ERCP pancreatitis in elderly10.1038/s41598-021-95484-82045-2322https://doaj.org/article/5c83d0f2fcab4ce88729b9499cf7e5362021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95484-8https://doaj.org/toc/2045-2322Abstract Post Endoscopic Retrograde Cholangiopancreatography (ERCP) pancreatitis is one of the most serious complications of ERCP. Our study aims to investigate the risk, predisposing factors and prognosis of pancreatitis after ERCP in elderly patients. Patients referred to the ERCP unit between April 2008 and 2012 and admitted to the hospital at least 1 day after the ERCP procedure were included to the study. Information including patient’s demographics, diagnosis, imaging findings, biochemical analysis, details of the ERCP procedure and complications were recorded. The severity of post ERCP pancreatitis (PEP) was determined by revised Atlanta Criteria as well as APACHE II and Ranson scores. A total of 2902 ERCP patients were evaluated and 988 were included to the study. Patients were divided into two groups as ≥ 65 years old (494 patients, 259 F, 235 M) and < 65 years old (494 patients, 274 F, 220 M). PEP was diagnosed in 4.3% of patients aged 65 years and older. The female gender was risk factors in elderly for PEP. The Sphincter Oddi Dysfunction (SOD) and Juxta papillary diverticula (JPD) were higher in elderly patients with PEP. Age did not increase the risk of PEP development. The most important post ERCP pancreatitis risk factor in the elderly is the female gender, while the risk is enhanced slightly by SOD and JPD.Erhan ErginNevin OruçGalip ErsözOktay TekeşinÖmer ÖzütemizNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Erhan Ergin Nevin Oruç Galip Ersöz Oktay Tekeşin Ömer Özütemiz Prognosis and risk factors of ERCP pancreatitis in elderly
description	Abstract Post Endoscopic Retrograde Cholangiopancreatography (ERCP) pancreatitis is one of the most serious complications of ERCP. Our study aims to investigate the risk, predisposing factors and prognosis of pancreatitis after ERCP in elderly patients. Patients referred to the ERCP unit between April 2008 and 2012 and admitted to the hospital at least 1 day after the ERCP procedure were included to the study. Information including patient’s demographics, diagnosis, imaging findings, biochemical analysis, details of the ERCP procedure and complications were recorded. The severity of post ERCP pancreatitis (PEP) was determined by revised Atlanta Criteria as well as APACHE II and Ranson scores. A total of 2902 ERCP patients were evaluated and 988 were included to the study. Patients were divided into two groups as ≥ 65 years old (494 patients, 259 F, 235 M) and < 65 years old (494 patients, 274 F, 220 M). PEP was diagnosed in 4.3% of patients aged 65 years and older. The female gender was risk factors in elderly for PEP. The Sphincter Oddi Dysfunction (SOD) and Juxta papillary diverticula (JPD) were higher in elderly patients with PEP. Age did not increase the risk of PEP development. The most important post ERCP pancreatitis risk factor in the elderly is the female gender, while the risk is enhanced slightly by SOD and JPD.
format	article
author	Erhan Ergin Nevin Oruç Galip Ersöz Oktay Tekeşin Ömer Özütemiz
author_facet	Erhan Ergin Nevin Oruç Galip Ersöz Oktay Tekeşin Ömer Özütemiz
author_sort	Erhan Ergin
title	Prognosis and risk factors of ERCP pancreatitis in elderly
title_short	Prognosis and risk factors of ERCP pancreatitis in elderly
title_full	Prognosis and risk factors of ERCP pancreatitis in elderly
title_fullStr	Prognosis and risk factors of ERCP pancreatitis in elderly
title_full_unstemmed	Prognosis and risk factors of ERCP pancreatitis in elderly
title_sort	prognosis and risk factors of ercp pancreatitis in elderly
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5c83d0f2fcab4ce88729b9499cf7e536
work_keys_str_mv	AT erhanergin prognosisandriskfactorsofercppancreatitisinelderly AT nevinoruc prognosisandriskfactorsofercppancreatitisinelderly AT galipersoz prognosisandriskfactorsofercppancreatitisinelderly AT oktaytekesin prognosisandriskfactorsofercppancreatitisinelderly AT omerozutemiz prognosisandriskfactorsofercppancreatitisinelderly
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Prognosis and risk factors of ERCP pancreatitis in elderly

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