Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.
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Nature Portfolio
2016
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oai:doaj.org-article:5c846e9746fc48718a23e4f9ead6ec8d2021-12-02T17:32:50ZFast, greener and scalable direct coupling of organolithium compounds with no additional solvents10.1038/ncomms116982041-1723https://doaj.org/article/5c846e9746fc48718a23e4f9ead6ec8d2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11698https://doaj.org/toc/2041-1723Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.Erik B. PinxterhuisMassimo GianneriniValentín HornillosBen L. FeringaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q Erik B. Pinxterhuis Massimo Giannerini Valentín Hornillos Ben L. Feringa Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
description |
Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes. |
format |
article |
author |
Erik B. Pinxterhuis Massimo Giannerini Valentín Hornillos Ben L. Feringa |
author_facet |
Erik B. Pinxterhuis Massimo Giannerini Valentín Hornillos Ben L. Feringa |
author_sort |
Erik B. Pinxterhuis |
title |
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
title_short |
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
title_full |
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
title_fullStr |
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
title_full_unstemmed |
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
title_sort |
fast, greener and scalable direct coupling of organolithium compounds with no additional solvents |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/5c846e9746fc48718a23e4f9ead6ec8d |
work_keys_str_mv |
AT erikbpinxterhuis fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents AT massimogiannerini fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents AT valentinhornillos fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents AT benlferinga fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents |
_version_ |
1718380187453751296 |