Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents

Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.

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Autores principales: Erik B. Pinxterhuis, Massimo Giannerini, Valentín Hornillos, Ben L. Feringa
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/5c846e9746fc48718a23e4f9ead6ec8d
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spelling oai:doaj.org-article:5c846e9746fc48718a23e4f9ead6ec8d2021-12-02T17:32:50ZFast, greener and scalable direct coupling of organolithium compounds with no additional solvents10.1038/ncomms116982041-1723https://doaj.org/article/5c846e9746fc48718a23e4f9ead6ec8d2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11698https://doaj.org/toc/2041-1723Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.Erik B. PinxterhuisMassimo GianneriniValentín HornillosBen L. FeringaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
description Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.
format article
author Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
author_facet Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
author_sort Erik B. Pinxterhuis
title Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_short Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_full Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_fullStr Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_full_unstemmed Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_sort fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/5c846e9746fc48718a23e4f9ead6ec8d
work_keys_str_mv AT erikbpinxterhuis fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT massimogiannerini fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT valentinhornillos fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT benlferinga fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
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