Medial preoptic area in mice is capable of mediating sexually dimorphic behaviors regardless of gender

The medial preoptic area (mPOA) in a mammalian brain is sexually dimorphic, and yet its exact function in mediating gender-specific behavior remains unclear. Here, Xu and colleagues show that optogenetic manipulation of the mPOA in male mice induce female-stereotyped behaviors and vice versa.

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Bibliographic Details
Main Authors: Yi-Chao Wei, Shao-Ran Wang, Zhuo-Lei Jiao, Wen Zhang, Jun-Kai Lin, Xing-Yu Li, Shuai-Shuai Li, Xin Zhang, Xiao-Hong Xu
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/5c8a42863cf8458e9acfa85861f1251f
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Summary:The medial preoptic area (mPOA) in a mammalian brain is sexually dimorphic, and yet its exact function in mediating gender-specific behavior remains unclear. Here, Xu and colleagues show that optogenetic manipulation of the mPOA in male mice induce female-stereotyped behaviors and vice versa.