Serum integrative omics reveals the landscape of human diabetic kidney disease

QR Code

Serum integrative omics reveals the landscape of human diabetic kidney disease

Objective: Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. Our study proposes to evaluate the diagnostic value of blood in monitoring the o...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Shijia Liu, Yuan Gui, Mark S. Wang, Lu Zhang, Tingting Xu, Yuchen Pan, Ke Zhang, Ying Yu, Liangxiang Xiao, Yi Qiao, Christopher Bonin, Geneva Hargis, Tao Huan, Yanbao Yu, Jianling Tao, Rong Zhang, Donald L. Kreutzer, Yanjiao Zhou, Xiao-Jun Tian, Yanlin Wang, Haiyan Fu, Xiaofei An, Silvia Liu, Dong Zhou
Format:	article
Langue:	EN
Publié:	Elsevier 2021
Sujets:	Diabetic kidney disease Type 2 diabetes mellitus Serum Proteomics Metabolomics Machine learning Internal medicine RC31-1245
Accès en ligne:	https://doaj.org/article/5c92b2d350eb4b5a838c01e88d8ffde6
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Multi-Omics Comparison of the Spontaneous Diabetes Mellitus and Diet-Induced Prediabetic Macaque Models
par: Zhu Yang, et autres
Publié: (2021)

Gas Chromatography–Mass Spectroscopy-Based Metabolomics Analysis Reveals Potential Biochemical Markers for Diagnosis of Gestational Diabetes Mellitus
par: Beata A. Raczkowska, et autres
Publié: (2021)

Omics Strategies in Current Advancements of Infectious Fish Disease Management
par: Maya Erna Natnan, et autres
Publié: (2021)

Revealing the Specific Regulations of Brassinolide on Tomato Fruit Chilling Injury by Integrated Multi-Omics
par: Chunmei Bai, et autres
Publié: (2021)

Metabolomic Profiling of Amino Acids in Human Plasma Distinguishes Diabetic Kidney Disease From Type 2 Diabetes Mellitus
par: Chunyu Zhou, et autres
Publié: (2021)

Association of Afamin Concentration with Type 1 and Type 2 Diabetes Mellitus
par: Rebwar Jalal Ali, et autres
Publié: (2021)

Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model
par: Florian Flenkenthaler, et autres
Publié: (2021)

Modulation of the Gut Microbiota during High-Dose Glycerol Monolaurate-Mediated Amelioration of Obesity in Mice Fed a High-Fat Diet
par: Minjie Zhao, et autres
Publié: (2020)

Multi-Omics Approach to Elucidate Cerebrospinal Fluid Changes in Dogs with Intervertebral Disc Herniation
par: Anita Horvatić, et autres
Publié: (2021)

Comprehensive Metabolomics Study in Children With Graves’ Disease
par: Qin Xia, et autres
Publié: (2021)

Multi-Omics Analysis Reveals Anti-<i>Staphylococcus aureus</i> Activity of Actinomycin D Originating from <i>Streptomyces parvulus</i>
par: Yuqi Lin, et autres
Publié: (2021)

Lysine Acetylation in the Proteome of Renal Tubular Epithelial Cells in Diabetic Nephropathy
par: Jiayi Wan, et autres
Publié: (2021)

Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet
par: Laura A. Cox, et autres
Publié: (2021)

Urinary Metabolomic Profile of Neonates Born to Women with Gestational Diabetes Mellitus
par: Ana Sofía Herrera-Van Oostdam, et autres
Publié: (2021)

Early Detection of Renal Impairment Among Patients with Type 2 Diabetes Mellitus Through Evaluation of Serum Cystatin C in Comparison with Serum Creatinine Levels: A Cross-Sectional Study
par: Asmamaw T, et autres
Publié: (2020)

Dysregulated Serum Lipid Metabolism Promotes the Occurrence and Development of Diabetic Retinopathy Associated With Upregulated Circulating Levels of VEGF-A, VEGF-D, and PlGF
par: Xinyuan Zhang, et autres
Publié: (2021)

Single-Cell Multiomics Analysis for Drug Discovery
par: Sam F. Nassar, et autres
Publié: (2021)

Metabolic Remodeling during Biofilm Development of <named-content content-type="genus-species">Bacillus subtilis</named-content>
par: Tippapha Pisithkul, et autres
Publié: (2019)

Medium & long-chain acylcarnitine’s relation to lipid metabolism as potential predictors for diabetic cardiomyopathy: a metabolomic study
par: Dan-meng Zheng, et autres
Publié: (2021)

Evaluation of serum lipid profile, body mass index, and waistline in Chinese patients with type 2 diabetes mellitus
par: Cui RT, et autres
Publié: (2016)

In situ Metabolomics of Metabolic Reprogramming Involved in a Mouse Model of Type 2 Diabetic Kidney Disease
par: Bai Linnan, et autres
Publié: (2021)

Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
par: Nadezhda Olegovna Lebedeva, et autres
Publié: (2012)

Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
par: Fernanda Rosa, et autres
Publié: (2021)

Gender-Specific Metabolomics Approach to Kidney Cancer
par: Stanisław Deja, et autres
Publié: (2021)

Serum Ferritin Independently Predicts the Incidence of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus
par: Wu YH, et autres
Publié: (2020)

A Label-Free Proteomic and Complementary Metabolomic Analysis of Leaves of the Resurrection Plant <i>Xerophyta</i> <i>schlechteri</i> during Dehydration
par: Hawwa Gabier, et autres
Publié: (2021)

The Role of Gut Microbiota and Microbiota-Related Serum Metabolites in the Progression of Diabetic Kidney Disease
par: Qing Zhang, et autres
Publié: (2021)

Correlation Between Serum Uric Acid Level and Central Body Fat Distribution in Patients with Type 2 Diabetes
par: Zong J, et autres
Publié: (2020)

Metoclopramide nanoparticles modulate immune response in a diabetic rat model: association with regulatory T cells and proinflammatory cytokines
par: Abd Ellah NH, et autres
Publié: (2019)

Relationship of the Phytosterols Intake and Serum Lipids in Patients with Diabetes Type II
par: A Kooshki, et autres
Publié: (2009)

UHPLC-MS-Based Serum and Urine Metabolomics Reveals the Anti-Diabetic Mechanism of Ginsenoside Re in Type 2 Diabetic Rats
par: Heyu Wang, et autres
Publié: (2021)

Urinary biomarkers for diagnosing poststroke depression in patients with type 2 diabetes mellitus
par: Liang ZH, et autres
Publié: (2019)

Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging
par: Zhonghua Wang, et autres
Publié: (2021)

Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
par: Dan Hao, et autres
Publié: (2021)

Associations of visit-to-visit variabilities and trajectories of serum lipids with the future probability of type 2 diabetes mellitus
par: Qian Sun, et autres
Publié: (2021)

Phocea, Pseudoflavonifractor and Lactobacillus intestinalis: Three Potential Biomarkers of Gut Microbiota That Affect Progression and Complications of Obesity-Induced Type 2 Diabetes Mellitus
par: Wang Y, et autres
Publié: (2020)

Possible Gender Influence in the Mechanisms Underlying the Oxidative Stress, Inflammatory Response, and the Metabolic Alterations in Patients with Obesity and/or Type 2 Diabetes
par: Martha Lucinda Contreras-Zentella, et autres
Publié: (2021)

MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses
par: Ernesto S. Nakayasu, et autres
Publié: (2016)

Local and systemic production of 45 cytokines in complicated proliferative diabetic retinopaty
par: V. V. Neroev, et autres
Publié: (2020)

Distinct Metabolomic Signatures in Preclinical and Obstructive Hypertrophic Cardiomyopathy
par: Maike Schuldt, et autres
Publié: (2021)