CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs

CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs

Off-target editing remains a concern for therapeutic applications of CRISPR-Cas9. Here the authors present CRISPR GUARD, which uses very short non-cleaving gRNAs to prevent editing at off-target sites.

Guardado en:
Detalles Bibliográficos
Autores principales: Matthew A. Coelho, Etienne De Braekeleer, Mike Firth, Michal Bista, Sebastian Lukasiak, Maria Emanuela Cuomo, Benjamin J. M. Taylor
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/5ca3e3c9d50c40859d3cc5b4b7665184
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares