MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura

Tang et al. show that microRNAs derived from an endoparasitic wasp Snellenius manilae bracovirus (SmBV), SmBV-miR-199b-5p and SmBV-miR-2989, target domeless and toll-7 in its host Spodoptera litura, suppressing the innate immune responses of parasitized hosts. This study provides insights into how p...

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Autores principales: Cheng-Kang Tang, Chih-Hsuan Tsai, Carol-P. Wu, Yu-Hsien Lin, Sung-Chan Wei, Yun-Heng Lu, Cheng-Hsun Li, Yueh-Lung Wu
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5ca7330a9a6a48938ab74d96915c44ad
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spelling oai:doaj.org-article:5ca7330a9a6a48938ab74d96915c44ad2021-12-02T11:45:59ZMicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura10.1038/s42003-020-01563-32399-3642https://doaj.org/article/5ca7330a9a6a48938ab74d96915c44ad2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01563-3https://doaj.org/toc/2399-3642Tang et al. show that microRNAs derived from an endoparasitic wasp Snellenius manilae bracovirus (SmBV), SmBV-miR-199b-5p and SmBV-miR-2989, target domeless and toll-7 in its host Spodoptera litura, suppressing the innate immune responses of parasitized hosts. This study provides insights into how parasites maximize their fitness by regulating host immunity.Cheng-Kang TangChih-Hsuan TsaiCarol-P. WuYu-Hsien LinSung-Chan WeiYun-Heng LuCheng-Hsun LiYueh-Lung WuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Cheng-Kang Tang
Chih-Hsuan Tsai
Carol-P. Wu
Yu-Hsien Lin
Sung-Chan Wei
Yun-Heng Lu
Cheng-Hsun Li
Yueh-Lung Wu
MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
description Tang et al. show that microRNAs derived from an endoparasitic wasp Snellenius manilae bracovirus (SmBV), SmBV-miR-199b-5p and SmBV-miR-2989, target domeless and toll-7 in its host Spodoptera litura, suppressing the innate immune responses of parasitized hosts. This study provides insights into how parasites maximize their fitness by regulating host immunity.
format article
author Cheng-Kang Tang
Chih-Hsuan Tsai
Carol-P. Wu
Yu-Hsien Lin
Sung-Chan Wei
Yun-Heng Lu
Cheng-Hsun Li
Yueh-Lung Wu
author_facet Cheng-Kang Tang
Chih-Hsuan Tsai
Carol-P. Wu
Yu-Hsien Lin
Sung-Chan Wei
Yun-Heng Lu
Cheng-Hsun Li
Yueh-Lung Wu
author_sort Cheng-Kang Tang
title MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
title_short MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
title_full MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
title_fullStr MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
title_full_unstemmed MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
title_sort micrornas from snellenius manilae bracovirus regulate innate and cellular immune responses of its host spodoptera litura
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5ca7330a9a6a48938ab74d96915c44ad
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