Utilizing digital pathology to quantify stromal caveolin-1 expression in malignant and benign ovarian tumors: Associations with clinicopathological parameters and clinical outcomes.

Utilizing digital pathology to quantify stromal caveolin-1 expression in malignant and benign ovarian tumors: Associations with clinicopathological parameters and clinical outcomes.

Loss of stromal caveolin-1 (Cav-1) is a biomarker of a cancer-associated fibroblast (CAF) phenotype and is related to progression, metastasis, and poor outcomes in several cancers. The objective of this study was to evaluate the clinical significance of Cav-1 expression in invasive epithelial ovaria...

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Main Authors: Daryoush Saeed-Vafa, Douglas C Marchion, Susan M McCarthy, Ardeshir Hakam, Alexis Lopez, Robert M Wenham, Sachin M Apte, Dung-Tsa Chen, Anthony M Magliocco, Johnathan M Lancaster, Brett M Reid, Jennifer B Permuth
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/5ca8a7d61e0f4af186e6fa6b2b9a9a6f
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https://doaj.org/article/5ca8a7d61e0f4af186e6fa6b2b9a9a6f

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