Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis
Ryan Dhindsa et al. conducted an exome-wide association study to identify a rare variant in SPDL1 as a risk factor for idiopathic pulmonary fibrosis (IPF). Their findings implicate mitotic checkpoint signalling as a new mechanism underlying IPF.
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Nature Portfolio
2021
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oai:doaj.org-article:5ca8ca31c47044f2a6b834855f2cbf1a2021-12-02T11:44:59ZIdentification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis10.1038/s42003-021-01910-y2399-3642https://doaj.org/article/5ca8ca31c47044f2a6b834855f2cbf1a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01910-yhttps://doaj.org/toc/2399-3642Ryan Dhindsa et al. conducted an exome-wide association study to identify a rare variant in SPDL1 as a risk factor for idiopathic pulmonary fibrosis (IPF). Their findings implicate mitotic checkpoint signalling as a new mechanism underlying IPF.Ryan S. DhindsaJohan MattssonAbhishek NagQuanli WangLouise V. WainRichard AllenEleanor M. WigmoreKristina IbanezDimitrios VitsiosSri V. V. DeeviSebastian WasilewskiMaria KarlssonGlenda LassiHenric OlssonDaniel MuthasSusan MonkleyAlex MackayLynne MurraySimon YoungCarolina HaefligerFinnGen ConsortiumToby M. MaherMaria G. BelvisiGisli JenkinsPhilip L. MolyneauxAdam PlattSlavé PetrovskiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Ryan S. Dhindsa Johan Mattsson Abhishek Nag Quanli Wang Louise V. Wain Richard Allen Eleanor M. Wigmore Kristina Ibanez Dimitrios Vitsios Sri V. V. Deevi Sebastian Wasilewski Maria Karlsson Glenda Lassi Henric Olsson Daniel Muthas Susan Monkley Alex Mackay Lynne Murray Simon Young Carolina Haefliger FinnGen Consortium Toby M. Maher Maria G. Belvisi Gisli Jenkins Philip L. Molyneaux Adam Platt Slavé Petrovski Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| description |
Ryan Dhindsa et al. conducted an exome-wide association study to identify a rare variant in SPDL1 as a risk factor for idiopathic pulmonary fibrosis (IPF). Their findings implicate mitotic checkpoint signalling as a new mechanism underlying IPF. |
| format |
article |
| author |
Ryan S. Dhindsa Johan Mattsson Abhishek Nag Quanli Wang Louise V. Wain Richard Allen Eleanor M. Wigmore Kristina Ibanez Dimitrios Vitsios Sri V. V. Deevi Sebastian Wasilewski Maria Karlsson Glenda Lassi Henric Olsson Daniel Muthas Susan Monkley Alex Mackay Lynne Murray Simon Young Carolina Haefliger FinnGen Consortium Toby M. Maher Maria G. Belvisi Gisli Jenkins Philip L. Molyneaux Adam Platt Slavé Petrovski |
| author_facet |
Ryan S. Dhindsa Johan Mattsson Abhishek Nag Quanli Wang Louise V. Wain Richard Allen Eleanor M. Wigmore Kristina Ibanez Dimitrios Vitsios Sri V. V. Deevi Sebastian Wasilewski Maria Karlsson Glenda Lassi Henric Olsson Daniel Muthas Susan Monkley Alex Mackay Lynne Murray Simon Young Carolina Haefliger FinnGen Consortium Toby M. Maher Maria G. Belvisi Gisli Jenkins Philip L. Molyneaux Adam Platt Slavé Petrovski |
| author_sort |
Ryan S. Dhindsa |
| title |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| title_short |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| title_full |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| title_fullStr |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| title_full_unstemmed |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis |
| title_sort |
identification of a missense variant in spdl1 associated with idiopathic pulmonary fibrosis |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/5ca8ca31c47044f2a6b834855f2cbf1a |
| work_keys_str_mv |
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