Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study

Mulu Ejigu,1 Zelalem Desalegn,2 Befirdu Mulatu,2 Getu Mosisa3 1CDC Project, East Wollega Zone Health Office, Nekemte, Oromia, Ethiopia; 2Department of Public Health, Institute of Health Science, Wollega University, Nekemte, Oromia, Ethiopia; 3School of Nursing and Midwifery, Institute of Health Scie...

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Autores principales:	Ejigu M, Desalegn Z, Mulatu B, Mosisa G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	hiv patient art combined art adherence nekemte specialized hospital Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/5caefc709a15437d8a28055c45f67d6e
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spelling	oai:doaj.org-article:5caefc709a15437d8a28055c45f67d6e2021-12-02T06:21:28ZAdherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study1179-1373https://doaj.org/article/5caefc709a15437d8a28055c45f67d6e2020-03-01T00:00:00Zhttps://www.dovepress.com/adherence-to-combined-antiretroviral-therapy-and-associated-factors-am-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Mulu Ejigu,1 Zelalem Desalegn,2 Befirdu Mulatu,2 Getu Mosisa3 1CDC Project, East Wollega Zone Health Office, Nekemte, Oromia, Ethiopia; 2Department of Public Health, Institute of Health Science, Wollega University, Nekemte, Oromia, Ethiopia; 3School of Nursing and Midwifery, Institute of Health Science, Wollega University, Nekemte, Oromia, EthiopiaCorrespondence: Zelalem Desalegn Email zolad09@gmail.comBackground: For people living with HIV, to have sustainable viral suppression and better clinical outcomes, they should have a high level of adherence to antiretroviral therapy. In the treatment of human immune deficiency, antiretroviral therapy adherence became the major challenge in both developed and developing countries. The level of antiretroviral therapy differs across the settings. This study aimed to assess the level of combined ART adherence and associated factors among adult people living with HIV attending Nekemte Specialized Hospital, Ethiopia.Methods: The institution-based cross-sectional quantitative study was conducted from August 2017 to September 2017. A total number of 284 clients participated in the study and a simple random sampling technique was used to allocate study participants. Data were entered into Excel and exported to SPSS version 20 for analysis. Bivariate analysis was conducted to identify candidate variables for multivariate analysis at p-value < 0.2. Multiple logistic regression analysis was conducted to determine the predictors of non-adherence to ART. P-value < 0.05 was considered to indicate statistical significance.Results: About 81% of the study participants adhered to combined anti-retroviral therapy. Mentioned reasons for missing ART medications were simply forgot to take medication (44.4%), lack of transportation (21%), to avoid side effects (11.4%), do not want significant others to notice taking medication (11.4%) and felt sick (11.4%). Not using reminder (AOR=4.98 (1.65, 15.02)), poor knowledge on ART (AOR=2.79 (1.49, 5.25)), and engaging in unprotected sexual intercourse (AOR=2.16 (1.15, 4.05)) were significantly associated with non-adherence to combined ART.Conclusion: About 81% of study participants adhered to combined ART, and poor knowledge about ART, engaging in unprotected sexual intercourse and not using the reminder were significantly associated with nonadherence to combined ART. Efforts to increase adherence levels should be encouraged.Keywords: HIV patient, ART, combined ART adherence, Nekemte Specialized HospitalEjigu MDesalegn ZMulatu BMosisa GDove Medical Pressarticlehiv patientartcombined art adherencenekemte specialized hospitalImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 12, Pp 97-106 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hiv patient art combined art adherence nekemte specialized hospital Immunologic diseases. Allergy RC581-607
spellingShingle	hiv patient art combined art adherence nekemte specialized hospital Immunologic diseases. Allergy RC581-607 Ejigu M Desalegn Z Mulatu B Mosisa G Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
description	Mulu Ejigu,1 Zelalem Desalegn,2 Befirdu Mulatu,2 Getu Mosisa3 1CDC Project, East Wollega Zone Health Office, Nekemte, Oromia, Ethiopia; 2Department of Public Health, Institute of Health Science, Wollega University, Nekemte, Oromia, Ethiopia; 3School of Nursing and Midwifery, Institute of Health Science, Wollega University, Nekemte, Oromia, EthiopiaCorrespondence: Zelalem Desalegn Email zolad09@gmail.comBackground: For people living with HIV, to have sustainable viral suppression and better clinical outcomes, they should have a high level of adherence to antiretroviral therapy. In the treatment of human immune deficiency, antiretroviral therapy adherence became the major challenge in both developed and developing countries. The level of antiretroviral therapy differs across the settings. This study aimed to assess the level of combined ART adherence and associated factors among adult people living with HIV attending Nekemte Specialized Hospital, Ethiopia.Methods: The institution-based cross-sectional quantitative study was conducted from August 2017 to September 2017. A total number of 284 clients participated in the study and a simple random sampling technique was used to allocate study participants. Data were entered into Excel and exported to SPSS version 20 for analysis. Bivariate analysis was conducted to identify candidate variables for multivariate analysis at p-value < 0.2. Multiple logistic regression analysis was conducted to determine the predictors of non-adherence to ART. P-value < 0.05 was considered to indicate statistical significance.Results: About 81% of the study participants adhered to combined anti-retroviral therapy. Mentioned reasons for missing ART medications were simply forgot to take medication (44.4%), lack of transportation (21%), to avoid side effects (11.4%), do not want significant others to notice taking medication (11.4%) and felt sick (11.4%). Not using reminder (AOR=4.98 (1.65, 15.02)), poor knowledge on ART (AOR=2.79 (1.49, 5.25)), and engaging in unprotected sexual intercourse (AOR=2.16 (1.15, 4.05)) were significantly associated with non-adherence to combined ART.Conclusion: About 81% of study participants adhered to combined ART, and poor knowledge about ART, engaging in unprotected sexual intercourse and not using the reminder were significantly associated with nonadherence to combined ART. Efforts to increase adherence levels should be encouraged.Keywords: HIV patient, ART, combined ART adherence, Nekemte Specialized Hospital
format	article
author	Ejigu M Desalegn Z Mulatu B Mosisa G
author_facet	Ejigu M Desalegn Z Mulatu B Mosisa G
author_sort	Ejigu M
title	Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
title_short	Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
title_full	Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
title_fullStr	Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
title_full_unstemmed	Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study
title_sort	adherence to combined antiretroviral therapy and associated factors among people living with hiv attending nekemte specialized hospital, oromia, ethiopia: a cross-sectional study
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/5caefc709a15437d8a28055c45f67d6e
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Adherence to Combined Antiretroviral Therapy and Associated Factors Among People Living with HIV Attending Nekemte Specialized Hospital, Oromia, Ethiopia: A Cross-Sectional Study

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