Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling

Long-range looping of an enhancer to a promoter (E-P looping) is a key feature of gene activation; thus, regulation of E-P looping could serve as an effective strategy to precisely control gene expression. Here the authors propose the Drosophila chromatin insulator antagonist Shep represses expressi...

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Autores principales: Dahong Chen, Catherine E. McManus, Behram Radmanesh, Leah H. Matzat, Elissa P. Lei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5cb314e949064507b4778645b69e034a
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