Partial Prion Cross-Seeding between Fungal and Mammalian Amyloid Signaling Motifs

Amyloids are β-sheet-rich protein polymers that can be pathological or display a variety of biological roles. In filamentous fungi, specific immune receptors activate programmed cell death execution proteins through a process of amyloid templating akin to prion propagation.

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Autores principales: Thierry Bardin, Asen Daskalov, Sophie Barrouilhet, Alexandra Granger-Farbos, Bénédicte Salin, Corinne Blancard, Brice Kauffmann, Sven J. Saupe, Virginie Coustou
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/5cb4282ddba348069a6d8cb745983ba6
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Sumario:Amyloids are β-sheet-rich protein polymers that can be pathological or display a variety of biological roles. In filamentous fungi, specific immune receptors activate programmed cell death execution proteins through a process of amyloid templating akin to prion propagation.