Irrelevance of microsatellite instability in the epidemiology of sporadic pancreatic ductal adenocarcinoma.

<h4>Background and aims</h4>Pancreatic cancer risk is increased in Lynch syndrome (LS) patients with mismatch repair gene defects predisposing to colonic and extracolonic cancers with microsatellite instability (MSI). However, the frequency of MSI pancreatic cancers has never been ascert...

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Auteurs principaux: Luigi Laghi, Stefania Beghelli, Antonino Spinelli, Paolo Bianchi, Gianluca Basso, Giuseppe Di Caro, Anna Brecht, Giuseppe Celesti, Giona Turri, Samantha Bersani, Guido Schumacher, Christoph Röcken, Ilona Gräntzdörffer, Massimo Roncalli, Alessandro Zerbi, Peter Neuhaus, Claudio Bassi, Marco Montorsi, Aldo Scarpa, Alberto Malesci
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
Q
Accès en ligne:https://doaj.org/article/5cb542163dfc4a388f1628bd23e5dc04
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