Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes

Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal ge...

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Autores principales: Gisela Di Venanzio, Ana L. Flores-Mireles, Juan J. Calix, M. Florencia Haurat, Nichollas E. Scott, Lauren D. Palmer, Robert F. Potter, Michael E. Hibbing, Laura Friedman, Bin Wang, Gautam Dantas, Eric P. Skaar, Scott J. Hultgren, Mario F. Feldman
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c243
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spelling oai:doaj.org-article:5cb55da71c7c462c8372f4c556e3c2432021-12-02T15:35:47ZUrinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes10.1038/s41467-019-10706-y2041-1723https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c2432019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10706-yhttps://doaj.org/toc/2041-1723Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal genes.Gisela Di VenanzioAna L. Flores-MirelesJuan J. CalixM. Florencia HauratNichollas E. ScottLauren D. PalmerRobert F. PotterMichael E. HibbingLaura FriedmanBin WangGautam DantasEric P. SkaarScott J. HultgrenMario F. FeldmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gisela Di Venanzio
Ana L. Flores-Mireles
Juan J. Calix
M. Florencia Haurat
Nichollas E. Scott
Lauren D. Palmer
Robert F. Potter
Michael E. Hibbing
Laura Friedman
Bin Wang
Gautam Dantas
Eric P. Skaar
Scott J. Hultgren
Mario F. Feldman
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
description Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal genes.
format article
author Gisela Di Venanzio
Ana L. Flores-Mireles
Juan J. Calix
M. Florencia Haurat
Nichollas E. Scott
Lauren D. Palmer
Robert F. Potter
Michael E. Hibbing
Laura Friedman
Bin Wang
Gautam Dantas
Eric P. Skaar
Scott J. Hultgren
Mario F. Feldman
author_facet Gisela Di Venanzio
Ana L. Flores-Mireles
Juan J. Calix
M. Florencia Haurat
Nichollas E. Scott
Lauren D. Palmer
Robert F. Potter
Michael E. Hibbing
Laura Friedman
Bin Wang
Gautam Dantas
Eric P. Skaar
Scott J. Hultgren
Mario F. Feldman
author_sort Gisela Di Venanzio
title Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
title_short Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
title_full Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
title_fullStr Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
title_full_unstemmed Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
title_sort urinary tract colonization is enhanced by a plasmid that regulates uropathogenic acinetobacter baumannii chromosomal genes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c243
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