Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes
Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal ge...
Guardado en:
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c243 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:5cb55da71c7c462c8372f4c556e3c243 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:5cb55da71c7c462c8372f4c556e3c2432021-12-02T15:35:47ZUrinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes10.1038/s41467-019-10706-y2041-1723https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c2432019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10706-yhttps://doaj.org/toc/2041-1723Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal genes.Gisela Di VenanzioAna L. Flores-MirelesJuan J. CalixM. Florencia HauratNichollas E. ScottLauren D. PalmerRobert F. PotterMichael E. HibbingLaura FriedmanBin WangGautam DantasEric P. SkaarScott J. HultgrenMario F. FeldmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Gisela Di Venanzio Ana L. Flores-Mireles Juan J. Calix M. Florencia Haurat Nichollas E. Scott Lauren D. Palmer Robert F. Potter Michael E. Hibbing Laura Friedman Bin Wang Gautam Dantas Eric P. Skaar Scott J. Hultgren Mario F. Feldman Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
description |
Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isolate by regulating the expression of chromosomal genes. |
format |
article |
author |
Gisela Di Venanzio Ana L. Flores-Mireles Juan J. Calix M. Florencia Haurat Nichollas E. Scott Lauren D. Palmer Robert F. Potter Michael E. Hibbing Laura Friedman Bin Wang Gautam Dantas Eric P. Skaar Scott J. Hultgren Mario F. Feldman |
author_facet |
Gisela Di Venanzio Ana L. Flores-Mireles Juan J. Calix M. Florencia Haurat Nichollas E. Scott Lauren D. Palmer Robert F. Potter Michael E. Hibbing Laura Friedman Bin Wang Gautam Dantas Eric P. Skaar Scott J. Hultgren Mario F. Feldman |
author_sort |
Gisela Di Venanzio |
title |
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
title_short |
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
title_full |
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
title_fullStr |
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
title_full_unstemmed |
Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes |
title_sort |
urinary tract colonization is enhanced by a plasmid that regulates uropathogenic acinetobacter baumannii chromosomal genes |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c243 |
work_keys_str_mv |
AT giseladivenanzio urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT analfloresmireles urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT juanjcalix urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT mflorenciahaurat urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT nichollasescott urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT laurendpalmer urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT robertfpotter urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT michaelehibbing urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT laurafriedman urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT binwang urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT gautamdantas urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT ericpskaar urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT scottjhultgren urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes AT marioffeldman urinarytractcolonizationisenhancedbyaplasmidthatregulatesuropathogenicacinetobacterbaumanniichromosomalgenes |
_version_ |
1718386475441061888 |