Fit-for-purpose quantitative liquid biopsy based droplet digital PCR assay development for detection of programmed cell death ligand-1 (PD-L1) RNA expression in PAXgene blood samples.

Development of a clinically applicable liquid biopsy-based test for PD-L1 mRNA expression would be beneficial in providing complementary evidence to current immunohistochemistry assays. Hence, we report the development of a fit-for-purpose assay for detection of blood PD-L1 mRNA expression using dro...

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Bibliographic Details
Main Authors: Dennis O'Rourke, Danyi Wang, Jorge F Sanchez-Garcia, Maria Perella Cusano, Waldemar Miller, Ti Cai, Juergen Scheuenpflug, Zheng Feng
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/5cb6fb0ac0a54dee8a6a076bc6158c73
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