The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity

Abstract Fat perception during eating is a complex sensation that involves various sensory modalities, such as texture, aroma and taste. Taste is supported by the discovery of fatty acid receptors in the tongue papillae. Dietary fat is mainly composed of esterified fatty acids, whereas only free fat...

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Autores principales:	Eric Neyraud, Stéphanie Cabaret, Hélène Brignot, Claire Chabanet, Hélène Labouré, Elisabeth Guichard, Olivier Berdeaux
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5cc2114d3a8c4833965aee9d61c079a8
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spelling	oai:doaj.org-article:5cc2114d3a8c4833965aee9d61c079a82021-12-02T15:06:09ZThe basal free fatty acid concentration in human saliva is related to salivary lipolytic activity10.1038/s41598-017-06418-22045-2322https://doaj.org/article/5cc2114d3a8c4833965aee9d61c079a82017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06418-2https://doaj.org/toc/2045-2322Abstract Fat perception during eating is a complex sensation that involves various sensory modalities, such as texture, aroma and taste. Taste is supported by the discovery of fatty acid receptors in the tongue papillae. Dietary fat is mainly composed of esterified fatty acids, whereas only free fatty acids can bind to taste receptors. Some authors have mentioned the necessity and efficiency of salivary lipolytic activity to hydrolyse the esterified fatty acids present in foods and enable fat perception. Our hypothesis is that salivary lipolytic activity is also involved in regulating the basal level of salivary fatty acids in humans. To test this hypothesis, total fatty acid (TFA) and free fatty acid (FFA) concentrations and selected salivary characteristics (such as lipolytic activity) were analysed in the resting saliva of 54 subjects. The results show differences in the TFA and FFA profiles, with TFA and FFA concentrations of 8.99 and 3.56 µg/mL of saliva, respectively. Interestingly, lipolytic activity had a significant positive correlation with FFA concentration (0.51, p < 0.01). This result highlights a possible physiological role of salivary lipolytic activity in the regulation of the basal FFA concentration. This regulation could be involved in fat taste sensitivity.Eric NeyraudStéphanie CabaretHélène BrignotClaire ChabanetHélène LabouréElisabeth GuichardOlivier BerdeauxNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Eric Neyraud Stéphanie Cabaret Hélène Brignot Claire Chabanet Hélène Labouré Elisabeth Guichard Olivier Berdeaux The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
description	Abstract Fat perception during eating is a complex sensation that involves various sensory modalities, such as texture, aroma and taste. Taste is supported by the discovery of fatty acid receptors in the tongue papillae. Dietary fat is mainly composed of esterified fatty acids, whereas only free fatty acids can bind to taste receptors. Some authors have mentioned the necessity and efficiency of salivary lipolytic activity to hydrolyse the esterified fatty acids present in foods and enable fat perception. Our hypothesis is that salivary lipolytic activity is also involved in regulating the basal level of salivary fatty acids in humans. To test this hypothesis, total fatty acid (TFA) and free fatty acid (FFA) concentrations and selected salivary characteristics (such as lipolytic activity) were analysed in the resting saliva of 54 subjects. The results show differences in the TFA and FFA profiles, with TFA and FFA concentrations of 8.99 and 3.56 µg/mL of saliva, respectively. Interestingly, lipolytic activity had a significant positive correlation with FFA concentration (0.51, p < 0.01). This result highlights a possible physiological role of salivary lipolytic activity in the regulation of the basal FFA concentration. This regulation could be involved in fat taste sensitivity.
format	article
author	Eric Neyraud Stéphanie Cabaret Hélène Brignot Claire Chabanet Hélène Labouré Elisabeth Guichard Olivier Berdeaux
author_facet	Eric Neyraud Stéphanie Cabaret Hélène Brignot Claire Chabanet Hélène Labouré Elisabeth Guichard Olivier Berdeaux
author_sort	Eric Neyraud
title	The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
title_short	The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
title_full	The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
title_fullStr	The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
title_full_unstemmed	The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
title_sort	basal free fatty acid concentration in human saliva is related to salivary lipolytic activity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5cc2114d3a8c4833965aee9d61c079a8
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The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity

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