ASSESSMENTS OF AUTOANTIBODY AND CYTOKINE CONTENTS IN TEENAGERS OF INDUSTRIAL CENTERS SCREENING EXAMINATION

270 teenagers without acute inflammation signs at the moment of the examination living in the industrial centers of Eastern Siberia have been examined. The declinations from the reference levels of the relative autoantibody content to native DNA were found to observe in 23.5 %, to β2-glycoprotein I...

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Auteurs principaux: L. B. Masnaviyeva, I. V. Kudayeva
Format: article
Langue:RU
Publié: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Accès en ligne:https://doaj.org/article/5cc238a3c87e46ec866f2651a2800408
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Résumé:270 teenagers without acute inflammation signs at the moment of the examination living in the industrial centers of Eastern Siberia have been examined. The declinations from the reference levels of the relative autoantibody content to native DNA were found to observe in 23.5 %, to β2-glycoprotein I — in 47.0 %, to Ig G Fc-fragment— in 31.3 % of the cases. It was revealed that gyperimmunoresponsiveness of the autoantibodies to β2- glycoprotein. I may be followed by the increase in the concentration of γ-interferon. The fluctuations of the of interleukin 2 and 10 contents and α-interferon in the dependence on the immunoresponsiveness were found to be in the range of the reference values.