Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles

Muhammad Qasim,1 Nopphadol Udomluck,1 Jihyun Chang,1 Hansoo Park,1 Kyobum Kim2 1School of Integrative Engineering, Chung-Ang University, Seoul, 2Division of Bioengineering, Incheon National University, Incheon, Republic of Korea Abstract: In this study, we analyzed the antimicrobial activities of...

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Autores principales:	Qasim M, Udomluck N, Chang J, Park H, Kim K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	pNIPAM Silver nanoparticles Antimicrobial activities Surface charge. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/5ccc40764f8a446985990c3ec9342c8d
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spelling	oai:doaj.org-article:5ccc40764f8a446985990c3ec9342c8d2021-12-02T01:23:33ZAntimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles1178-2013https://doaj.org/article/5ccc40764f8a446985990c3ec9342c8d2018-01-01T00:00:00Zhttps://www.dovepress.com/antimicrobial-activity-of-silver-nanoparticles-encapsulated-in-poly-n--peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Muhammad Qasim,1 Nopphadol Udomluck,1 Jihyun Chang,1 Hansoo Park,1 Kyobum Kim2 1School of Integrative Engineering, Chung-Ang University, Seoul, 2Division of Bioengineering, Incheon National University, Incheon, Republic of Korea Abstract: In this study, we analyzed the antimicrobial activities of poly-N-isopropylacrylamide (pNIPAM)-based polymeric nanoparticles encapsulating silver nanoparticles (AgNPs). Three sizes of AgNP-encapsulating pNIPAM- and pNIPAM-NH2-based polymeric nanoparticles were fabricated. Highly stable and uniformly distributed AgNPs were encapsulated within polymeric nanoparticles via in situ reduction of AgNO3 using NaBH4 as the reducing agent. The formation and distribution of AgNPs was confirmed by UV-visible spectroscopy, transmission electron microscopy, and inductively coupled plasma optical emission spectrometry, respectively. Both polymeric nanoparticles showed significant bacteriostatic activities against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria depending on the nanoparticle size and amount of AgNO3 used during fabrication. Keywords: pNIPAM, silver nanoparticles, antimicrobial activities, surface chargeQasim MUdomluck NChang JPark HKim KDove Medical PressarticlepNIPAMSilver nanoparticlesAntimicrobial activitiesSurface charge.Medicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 235-249 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	pNIPAM Silver nanoparticles Antimicrobial activities Surface charge. Medicine (General) R5-920
spellingShingle	pNIPAM Silver nanoparticles Antimicrobial activities Surface charge. Medicine (General) R5-920 Qasim M Udomluck N Chang J Park H Kim K Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
description	Muhammad Qasim,1 Nopphadol Udomluck,1 Jihyun Chang,1 Hansoo Park,1 Kyobum Kim2 1School of Integrative Engineering, Chung-Ang University, Seoul, 2Division of Bioengineering, Incheon National University, Incheon, Republic of Korea Abstract: In this study, we analyzed the antimicrobial activities of poly-N-isopropylacrylamide (pNIPAM)-based polymeric nanoparticles encapsulating silver nanoparticles (AgNPs). Three sizes of AgNP-encapsulating pNIPAM- and pNIPAM-NH2-based polymeric nanoparticles were fabricated. Highly stable and uniformly distributed AgNPs were encapsulated within polymeric nanoparticles via in situ reduction of AgNO3 using NaBH4 as the reducing agent. The formation and distribution of AgNPs was confirmed by UV-visible spectroscopy, transmission electron microscopy, and inductively coupled plasma optical emission spectrometry, respectively. Both polymeric nanoparticles showed significant bacteriostatic activities against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria depending on the nanoparticle size and amount of AgNO3 used during fabrication. Keywords: pNIPAM, silver nanoparticles, antimicrobial activities, surface charge
format	article
author	Qasim M Udomluck N Chang J Park H Kim K
author_facet	Qasim M Udomluck N Chang J Park H Kim K
author_sort	Qasim M
title	Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
title_short	Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
title_full	Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
title_fullStr	Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
title_full_unstemmed	Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
title_sort	antimicrobial activity of silver nanoparticles encapsulated in poly-n-isopropylacrylamide-based polymeric nanoparticles
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/5ccc40764f8a446985990c3ec9342c8d
work_keys_str_mv	AT qasimm antimicrobialactivityofsilvernanoparticlesencapsulatedinpolynisopropylacrylamidebasedpolymericnanoparticles AT udomluckn antimicrobialactivityofsilvernanoparticlesencapsulatedinpolynisopropylacrylamidebasedpolymericnanoparticles AT changj antimicrobialactivityofsilvernanoparticlesencapsulatedinpolynisopropylacrylamidebasedpolymericnanoparticles AT parkh antimicrobialactivityofsilvernanoparticlesencapsulatedinpolynisopropylacrylamidebasedpolymericnanoparticles AT kimk antimicrobialactivityofsilvernanoparticlesencapsulatedinpolynisopropylacrylamidebasedpolymericnanoparticles
_version_	1718403140155342848

Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles

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