Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway
Excess body weight is thought to increase the risk of aggressive prostate cancer (PCa), although the biological mechanism is currently unclear. Body fatness is positively associated with a diminished cellular response to insulin and biomarkers of insulin signalling have been positively associated wi...
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Autores principales: | Rachel James, Olympia Dimopoulou, Richard M. Martin, Claire M. Perks, Claire Kelly, Louise Mathias, Stefan Brugger, Julian P. T. Higgins, Sarah J. Lewis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5ccd3efcf43148d0abb8d35c7c7b07e4 |
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