Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombosis and pregnancy morbidity (PM) obstetric events together with persistent high titers of circulating antiphospholipid antibodies (aPL). Several mechanisms that explain the development of thrombosis and PM in APS includ...

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Bibliographic Details
Main Authors: Carlos M. Rodríguez, Manuela Velásquez-Berrío, Carolina Rúa, Marta Viana, Vikki M. Abrahams, Angela P. Cadavid, Angela M. Alvarez
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/5cda4908e2864e92a72bbf752980992b
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