Glutamine deprivation triggers NAGK-dependent hexosamine salvage

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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylation in the cell. Prior studies have identified the...

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Auteurs principaux:	Sydney Campbell, Clementina Mesaros, Luke Izzo, Hayley Affronti, Michael Noji, Bethany E Schaffer, Tiffany Tsang, Kathryn Sun, Sophie Trefely, Salisa Kruijning, John Blenis, Ian A Blair, Kathryn E Wellen
Format:	article
Langue:	EN
Publié:	eLife Sciences Publications Ltd 2021
Sujets:	hexosamine pancreatic cancer N-acetylglucosamine kinase glutamine Medicine R Science Q Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/5ce0bca35ac845fba57a2e6f6f790030
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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