Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury.
Transglutaminase 2 (TG2) is a multifunctional mammalian protein with transamidase and signaling properties. Using selective TG2 inhibitors and tagged nucleophilic amine substrates, we show that the majority of extracellular TG2 is inactive under normal physiological conditions in cell culture and in...
Guardado en:
Autores principales: | Matthew Siegel, Pavel Strnad, R Edward Watts, Kihang Choi, Bana Jabri, M Bishr Omary, Chaitan Khosla |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/5cf5c1b6f2524e95bdbec9e682de5187 |
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