Current Therapeutic Strategies and Prospects for EGFR Mutation-Positive Lung Cancer Based on the Mechanisms Underlying Drug Resistance

The discovery of activating mutations in the epidermal growth factor receptor (<i>EGFR</i>) gene and the development of EGFR tyrosine kinase inhibitors (TKIs) have led to a paradigm shift in the treatment of non-small cell lung cancer (NSCLC). <i>EGFR</i> mutation-positive NS...

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Bibliographic Details
Main Authors: Yukari Tsubata, Ryosuke Tanino, Takeshi Isobe
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/5cfa5435b6c34b2f8549d7967e087ca1
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