Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis

Liver sinusoidal endothelial cells are known to promote immune tolerance in liver. Here, the authors target these cells using melittin nanoparticles and show alterations in the liver immune environment and suppression of liver metastases.

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Autores principales: Xiang Yu, Lu Chen, Jianqiao Liu, Bolei Dai, Guoqiang Xu, Guanxin Shen, Qingming Luo, Zhihong Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5d0b2877b338435fb23f97db1645c85f
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spelling oai:doaj.org-article:5d0b2877b338435fb23f97db1645c85f2021-12-02T17:33:11ZImmune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis10.1038/s41467-019-08538-x2041-1723https://doaj.org/article/5d0b2877b338435fb23f97db1645c85f2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08538-xhttps://doaj.org/toc/2041-1723Liver sinusoidal endothelial cells are known to promote immune tolerance in liver. Here, the authors target these cells using melittin nanoparticles and show alterations in the liver immune environment and suppression of liver metastases.Xiang YuLu ChenJianqiao LiuBolei DaiGuoqiang XuGuanxin ShenQingming LuoZhihong ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiang Yu
Lu Chen
Jianqiao Liu
Bolei Dai
Guoqiang Xu
Guanxin Shen
Qingming Luo
Zhihong Zhang
Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
description Liver sinusoidal endothelial cells are known to promote immune tolerance in liver. Here, the authors target these cells using melittin nanoparticles and show alterations in the liver immune environment and suppression of liver metastases.
format article
author Xiang Yu
Lu Chen
Jianqiao Liu
Bolei Dai
Guoqiang Xu
Guanxin Shen
Qingming Luo
Zhihong Zhang
author_facet Xiang Yu
Lu Chen
Jianqiao Liu
Bolei Dai
Guoqiang Xu
Guanxin Shen
Qingming Luo
Zhihong Zhang
author_sort Xiang Yu
title Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
title_short Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
title_full Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
title_fullStr Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
title_full_unstemmed Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
title_sort immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/5d0b2877b338435fb23f97db1645c85f
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AT boleidai immunemodulationofliversinusoidalendothelialcellsbymelittinnanoparticlessuppresseslivermetastasis
AT guoqiangxu immunemodulationofliversinusoidalendothelialcellsbymelittinnanoparticlessuppresseslivermetastasis
AT guanxinshen immunemodulationofliversinusoidalendothelialcellsbymelittinnanoparticlessuppresseslivermetastasis
AT qingmingluo immunemodulationofliversinusoidalendothelialcellsbymelittinnanoparticlessuppresseslivermetastasis
AT zhihongzhang immunemodulationofliversinusoidalendothelialcellsbymelittinnanoparticlessuppresseslivermetastasis
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