The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion

Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components. MUC1 is a large transmembrane glycoprotein expressed by most epithelial cells that can have direct defensive or receptor functions at...

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Autores principales:	Xinyue Li, Richard W. Wubbolts, Nancy M. C. Bleumink-Pluym, Jos P. M. van Putten, Karin Strijbis
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/5d0ddbad58f845aabd7df23c0ebc0e40
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spelling	oai:doaj.org-article:5d0ddbad58f845aabd7df23c0ebc0e402021-11-03T18:56:09ZThe Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion2150-751110.1128/mBio.03491-20https://doaj.org/article/5d0ddbad58f845aabd7df23c0ebc0e402021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03491-20https://doaj.org/toc/2150-7511 Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components. MUC1 is a large transmembrane glycoprotein expressed by most epithelial cells that can have direct defensive or receptor functions at the host-microbe interface and is involved in facilitating integrin clustering.Xinyue LiRichard W. WubboltsNancy M. C. Bleumink-PluymJos P. M. van PuttenKarin StrijbisAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Xinyue Li Richard W. Wubbolts Nancy M. C. Bleumink-Pluym Jos P. M. van Putten Karin Strijbis The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
description	Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components. MUC1 is a large transmembrane glycoprotein expressed by most epithelial cells that can have direct defensive or receptor functions at the host-microbe interface and is involved in facilitating integrin clustering.
format	article
author	Xinyue Li Richard W. Wubbolts Nancy M. C. Bleumink-Pluym Jos P. M. van Putten Karin Strijbis
author_facet	Xinyue Li Richard W. Wubbolts Nancy M. C. Bleumink-Pluym Jos P. M. van Putten Karin Strijbis
author_sort	Xinyue Li
title	The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
title_short	The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
title_full	The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
title_fullStr	The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
title_full_unstemmed	The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
title_sort	transmembrane mucin muc1 facilitates β1-integrin-mediated bacterial invasion
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/5d0ddbad58f845aabd7df23c0ebc0e40
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The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion

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