The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion

Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components. MUC1 is a large transmembrane glycoprotein expressed by most epithelial cells that can have direct defensive or receptor functions at...

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Bibliographic Details
Main Authors: Xinyue Li, Richard W. Wubbolts, Nancy M. C. Bleumink-Pluym, Jos P. M. van Putten, Karin Strijbis
Format: article
Language:EN
Published: American Society for Microbiology 2021
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Online Access:https://doaj.org/article/5d0ddbad58f845aabd7df23c0ebc0e40
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