Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis

Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis

The mechanisms controlling irreversible cell cycle exit in cerebellar granule progenitors (GCPs) have not been fully elucidated. Here, the authors performed RNA-sequencing of GCPs exiting the cell cycle to identify downregulation of Brd4 activity as an early event during cell cycle exit which subseq...

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Autores principales: Clara Penas, Marie E. Maloof, Vasileios Stathias, Jun Long, Sze Kiat Tan, Jose Mier, Yin Fang, Camilo Valdes, Jezabel Rodriguez-Blanco, Cheng-Ming Chiang, David J. Robbins, Daniel J. Liebl, Jae K. Lee, Mary E. Hatten, Jennifer Clarke, Nagi G. Ayad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/5d102d486ad049ca91e993219a553e49
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https://doaj.org/article/5d102d486ad049ca91e993219a553e49

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