FAK signalling controls insulin sensitivity through regulation of adipocyte survival

The kinase FAK is important for integrin signalling and promotes cell survival. Here, the authors demonstrate FAK regulates adipocyte survival, and is particularly important for maintaining insulin sensitivity during adipose tissue expansion in the context of a calorie-rich diet.

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Autores principales:	Cynthia T. Luk, Sally Yu Shi, Erica P. Cai, Tharini Sivasubramaniyam, Mansa Krishnamurthy, Jara J. Brunt, Stephanie A. Schroer, Daniel A. Winer, Minna Woo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5d165920dc0744d7a47a01caacc2dd90
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spelling	oai:doaj.org-article:5d165920dc0744d7a47a01caacc2dd902021-12-02T14:41:11ZFAK signalling controls insulin sensitivity through regulation of adipocyte survival10.1038/ncomms143602041-1723https://doaj.org/article/5d165920dc0744d7a47a01caacc2dd902017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14360https://doaj.org/toc/2041-1723The kinase FAK is important for integrin signalling and promotes cell survival. Here, the authors demonstrate FAK regulates adipocyte survival, and is particularly important for maintaining insulin sensitivity during adipose tissue expansion in the context of a calorie-rich diet.Cynthia T. LukSally Yu ShiErica P. CaiTharini SivasubramaniyamMansa KrishnamurthyJara J. BruntStephanie A. SchroerDaniel A. WinerMinna WooNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cynthia T. Luk Sally Yu Shi Erica P. Cai Tharini Sivasubramaniyam Mansa Krishnamurthy Jara J. Brunt Stephanie A. Schroer Daniel A. Winer Minna Woo FAK signalling controls insulin sensitivity through regulation of adipocyte survival
description	The kinase FAK is important for integrin signalling and promotes cell survival. Here, the authors demonstrate FAK regulates adipocyte survival, and is particularly important for maintaining insulin sensitivity during adipose tissue expansion in the context of a calorie-rich diet.
format	article
author	Cynthia T. Luk Sally Yu Shi Erica P. Cai Tharini Sivasubramaniyam Mansa Krishnamurthy Jara J. Brunt Stephanie A. Schroer Daniel A. Winer Minna Woo
author_facet	Cynthia T. Luk Sally Yu Shi Erica P. Cai Tharini Sivasubramaniyam Mansa Krishnamurthy Jara J. Brunt Stephanie A. Schroer Daniel A. Winer Minna Woo
author_sort	Cynthia T. Luk
title	FAK signalling controls insulin sensitivity through regulation of adipocyte survival
title_short	FAK signalling controls insulin sensitivity through regulation of adipocyte survival
title_full	FAK signalling controls insulin sensitivity through regulation of adipocyte survival
title_fullStr	FAK signalling controls insulin sensitivity through regulation of adipocyte survival
title_full_unstemmed	FAK signalling controls insulin sensitivity through regulation of adipocyte survival
title_sort	fak signalling controls insulin sensitivity through regulation of adipocyte survival
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5d165920dc0744d7a47a01caacc2dd90
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FAK signalling controls insulin sensitivity through regulation of adipocyte survival

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