Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia

Aims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participatio...

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Autores principales:	Olga Nikolaevna Bondarenko, N L Ayubova, Gagik Radikovich Galstyan, Ivan Ivanovich Dedov
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2013
Materias:	transcutaneous oximetry critical limb ischemia percutaneous transluminal balloon angioplasty diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/5d287fb981ba46cbaaad0e80bfd7b1a4
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spelling	oai:doaj.org-article:5d287fb981ba46cbaaad0e80bfd7b1a42021-11-14T09:00:18ZTranscutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia2072-03512072-037810.14341/2072-0351-3594https://doaj.org/article/5d287fb981ba46cbaaad0e80bfd7b1a42013-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/3594https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participation in this study (148 limbs in total). 22 patients underwent PTBA on both lower limbs, and 104 ? on single limb. Transcutaneous oximetry and duplex ultrasonography of lower limb arteries was performed prior to PTBA with subsequent examinations on 5-7th days, 1st, 3rd and 6th month after intervention. Transcu- taneous oxygen tension (TcpO2) was measured by Radiometer (Copenhagen) oximeter system. Duplex ultrasonography was performed on Voluson 730? Expert system (GE Medical Systems Kretztechnik GmbH&Co OHG, Austria). Results. Multiple factor analysis suggests that results of TcpO2 monitoring prior to and after PTBA are influenced by presence of ischemic heart disease, severe lower limb infections, serum creatinine, arterial hypertension and lower limb reperfusion edema. We observed a strong correlation of TcpO2 with the degree of anterior tibial artery and dorsal pedis artery occlusion. Conclusion. Transcutaneous oximetry allows evaluation of CLI severity and efficiency of PTBA in the majority oа patients with DM and CLI. Certain comorbidities impose limitations on this technique. Efficiency of endovascular intervention should be evaluated based on complex non-invasive examination, clinical data and signs of CLI.Olga Nikolaevna BondarenkoN L AyubovaGagik Radikovich GalstyanIvan Ivanovich DedovEndocrinology Research Centrearticletranscutaneous oximetrycritical limb ischemiapercutaneous transluminal balloon angioplastydiabetes mellitusNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 1, Pp 33-42 (2013)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	transcutaneous oximetry critical limb ischemia percutaneous transluminal balloon angioplasty diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	transcutaneous oximetry critical limb ischemia percutaneous transluminal balloon angioplasty diabetes mellitus Nutritional diseases. Deficiency diseases RC620-627 Olga Nikolaevna Bondarenko N L Ayubova Gagik Radikovich Galstyan Ivan Ivanovich Dedov Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
description	Aims. To evaluate transcutaneous oximetry as a method for diagnostics and monitoring in patients with diabetes mellitus (DM) and critical limb ischemia (CLI) after percutaneous transluminal balloon angioplasty (PTBA). Materials and Methods. We enrolled 126 patients with DM and CLI for participation in this study (148 limbs in total). 22 patients underwent PTBA on both lower limbs, and 104 ? on single limb. Transcutaneous oximetry and duplex ultrasonography of lower limb arteries was performed prior to PTBA with subsequent examinations on 5-7th days, 1st, 3rd and 6th month after intervention. Transcu- taneous oxygen tension (TcpO2) was measured by Radiometer (Copenhagen) oximeter system. Duplex ultrasonography was performed on Voluson 730? Expert system (GE Medical Systems Kretztechnik GmbH&Co OHG, Austria). Results. Multiple factor analysis suggests that results of TcpO2 monitoring prior to and after PTBA are influenced by presence of ischemic heart disease, severe lower limb infections, serum creatinine, arterial hypertension and lower limb reperfusion edema. We observed a strong correlation of TcpO2 with the degree of anterior tibial artery and dorsal pedis artery occlusion. Conclusion. Transcutaneous oximetry allows evaluation of CLI severity and efficiency of PTBA in the majority oа patients with DM and CLI. Certain comorbidities impose limitations on this technique. Efficiency of endovascular intervention should be evaluated based on complex non-invasive examination, clinical data and signs of CLI.
format	article
author	Olga Nikolaevna Bondarenko N L Ayubova Gagik Radikovich Galstyan Ivan Ivanovich Dedov
author_facet	Olga Nikolaevna Bondarenko N L Ayubova Gagik Radikovich Galstyan Ivan Ivanovich Dedov
author_sort	Olga Nikolaevna Bondarenko
title	Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_short	Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_full	Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_fullStr	Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_full_unstemmed	Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
title_sort	transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia
publisher	Endocrinology Research Centre
publishDate	2013
url	https://doaj.org/article/5d287fb981ba46cbaaad0e80bfd7b1a4
work_keys_str_mv	AT olganikolaevnabondarenko transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia AT nlayubova transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia AT gagikradikovichgalstyan transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia AT ivanivanovichdedov transcutaneousoximetrymonitoringinpatientswithtype2diabetesmellitusandcriticallimbischemia
_version_	1718429582857601024

Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia

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