A dual-target molecular mechanism of pyrethrum repellency against mosquitoes

A dual-target molecular mechanism of pyrethrum repellency against mosquitoes

Although pyrethrum is used to repel insects for centuries, the underlying mechanism has been enigmatic. Liu et al. found that specific components of pyrethrum mediate repellency by targeting olfactory receptors and/or voltage-gated sodium channels in Aedes aegypti mosquitoes.

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Bibliographic Details
Main Authors: Feng Liu, Qiang Wang, Peng Xu, Felipe Andreazza, Wilson R. Valbon, Elizabeth Bandason, Mengli Chen, Ru Yan, Bo Feng, Leticia B. Smith, Jeffrey G. Scott, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, James Klimavicz, Joel Coats, Eugenio E. Oliveira, Yuzhe Du, Ke Dong
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/5d3f109d9e214b4ba1f8ec0e86376c4a
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Summary:Although pyrethrum is used to repel insects for centuries, the underlying mechanism has been enigmatic. Liu et al. found that specific components of pyrethrum mediate repellency by targeting olfactory receptors and/or voltage-gated sodium channels in Aedes aegypti mosquitoes.

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