An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data

An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data

Genome-wide chromosome conformation capture has helped us identify features of genome topology influencing biology but requires careful statistical analysis. Here the authors present HiC-DC, a bioinformatics method that can detect statistically significant regulatory interactions.

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Detalles Bibliográficos
Autores principales: Mark Carty, Lee Zamparo, Merve Sahin, Alvaro González, Raphael Pelossof, Olivier Elemento, Christina S. Leslie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/5d47fe47c7bf4ef0ad411c538d7ab7a4
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