Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo

In superficial layers of the cortex, excitatory neurons often fire single action potentials. Here, using multiple whole-cell recordings in vivo, the authors show that single excitatory synaptic events can drive GABA-ergic parvalbumin neurons to fire, triggering inhibition of other pyramidal neurons.

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Autores principales:	Jean-Sébastien Jouhanneau, Jens Kremkow, James F. A. Poulet
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5d5169fe1eae463dae7772c078ef76cd
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spelling	oai:doaj.org-article:5d5169fe1eae463dae7772c078ef76cd2021-12-02T15:34:18ZSingle synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo10.1038/s41467-018-03995-22041-1723https://doaj.org/article/5d5169fe1eae463dae7772c078ef76cd2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03995-2https://doaj.org/toc/2041-1723In superficial layers of the cortex, excitatory neurons often fire single action potentials. Here, using multiple whole-cell recordings in vivo, the authors show that single excitatory synaptic events can drive GABA-ergic parvalbumin neurons to fire, triggering inhibition of other pyramidal neurons.Jean-Sébastien JouhanneauJens KremkowJames F. A. PouletNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jean-Sébastien Jouhanneau Jens Kremkow James F. A. Poulet Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
description	In superficial layers of the cortex, excitatory neurons often fire single action potentials. Here, using multiple whole-cell recordings in vivo, the authors show that single excitatory synaptic events can drive GABA-ergic parvalbumin neurons to fire, triggering inhibition of other pyramidal neurons.
format	article
author	Jean-Sébastien Jouhanneau Jens Kremkow James F. A. Poulet
author_facet	Jean-Sébastien Jouhanneau Jens Kremkow James F. A. Poulet
author_sort	Jean-Sébastien Jouhanneau
title	Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
title_short	Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
title_full	Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
title_fullStr	Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
title_full_unstemmed	Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo
title_sort	single synaptic inputs drive high-precision action potentials in parvalbumin expressing gaba-ergic cortical neurons in vivo
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5d5169fe1eae463dae7772c078ef76cd
work_keys_str_mv	AT jeansebastienjouhanneau singlesynapticinputsdrivehighprecisionactionpotentialsinparvalbuminexpressinggabaergiccorticalneuronsinvivo AT jenskremkow singlesynapticinputsdrivehighprecisionactionpotentialsinparvalbuminexpressinggabaergiccorticalneuronsinvivo AT jamesfapoulet singlesynapticinputsdrivehighprecisionactionpotentialsinparvalbuminexpressinggabaergiccorticalneuronsinvivo
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Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo

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