Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach.
Large-scale genomic alterations play an important role in disease, gene expression, and chromosome evolution. Optical DNA mapping (ODM), commonly categorized into sparsely-labelled ODM and densely-labelled ODM, provides sequence-specific continuous intensity profiles (DNA barcodes) along single DNA...
Guardado en:
Autores principales: | Albertas Dvirnas, Callum Stewart, Vilhelm Müller, Santosh Kumar Bikkarolla, Karolin Frykholm, Linus Sandegren, Erik Kristiansson, Fredrik Westerlund, Tobias Ambjörnsson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5d51b3569c7f4932b048a6015027f32e |
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