Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach.

Large-scale genomic alterations play an important role in disease, gene expression, and chromosome evolution. Optical DNA mapping (ODM), commonly categorized into sparsely-labelled ODM and densely-labelled ODM, provides sequence-specific continuous intensity profiles (DNA barcodes) along single DNA...

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Autores principales:	Albertas Dvirnas, Callum Stewart, Vilhelm Müller, Santosh Kumar Bikkarolla, Karolin Frykholm, Linus Sandegren, Erik Kristiansson, Fredrik Westerlund, Tobias Ambjörnsson
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5d51b3569c7f4932b048a6015027f32e
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Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach

por Albertas Dvirnas, Callum Stewart, Vilhelm Müller, Santosh Kumar Bikkarolla, Karolin Frykholm, Linus Sandegren, Erik Kristiansson, Fredrik Westerlund, Tobias Ambjörnsson
Publicado 2021

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Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach.

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