Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice

Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice

Abstract Maternal high-fat diet (HFD) alters hypothalamic developmental programming and disrupts offspring energy homeostasis in rodents. 17β-estradiol (E2) also influences hypothalamic programming through estrogen receptor (ER) α. Therefore, we hypothesized that females lacking ERα would be more su...

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Autores principales: Troy A. Roepke, Ali Yasrebi, Alejandra Villalobos, Elizabeth A. Krumm, Jennifer A. Yang, Kyle J. Mamounis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5d584998040a4876b65ce071130d2172
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