Epidemiology of lung cancer

Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the second most common cancer diagnosis in men and women (after prostate and breast cancer, respectively). With increasing acc...

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Autores principales: Krishna Chaitanya Thandra, Adam Barsouk, Kalyan Saginala, John Sukumar Aluru, Alexander Barsouk
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Lenguaje:EN
Publicado: Termedia Publishing House 2021
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Acceso en línea:https://doaj.org/article/5d63ebf684d04f7fbe13fb2f73b44c40
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spelling oai:doaj.org-article:5d63ebf684d04f7fbe13fb2f73b44c402021-12-02T17:45:58ZEpidemiology of lung cancer1428-25261897-430910.5114/wo.2021.103829https://doaj.org/article/5d63ebf684d04f7fbe13fb2f73b44c402021-02-01T00:00:00Zhttps://www.termedia.pl/Epidemiology-of-lung-cancer,3,43345,1,1.htmlhttps://doaj.org/toc/1428-2526https://doaj.org/toc/1897-4309Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the second most common cancer diagnosis in men and women (after prostate and breast cancer, respectively). With increasing access to tobacco and industrialization in developing nations, lung cancer incidence is rising globally. The average age of diagnosis is 70 years old. Men are twice as likely to be diagnosed with lung cancer, which largely reflects differences in tobacco consumption, although women may be more susceptible due to higher proportions of epidermal growth factor receptor mutations and the effects of oestrogen. African American men in the US are at the highest risk of lung cancer. Family history increases risk by 1.7-fold, with a greater risk among first-degree relatives. Tobacco smoking is the greatest preventable cause of death worldwide, accounting for up to 90% of lung cancer cases, and continued consumption is projected to increase global cancer incidence, particularly in developing nations such as China, Russia, and India. Second-hand smoke among children and spouses has likewise been implicated. Radon from natural underground uranium decay is the second leading cause of lung cancer in the developed world. Occupational hazards such as asbestos and environmental exposures such as air pollution, arsenic, and HIV and Tb infection have all been implicated in lung carcinogenesis, while cannabis smoking, electronic cigarettes, heated tobacco products, and COVID-19 have been hypothesized to increase risk.Krishna Chaitanya ThandraAdam BarsoukKalyan SaginalaJohn Sukumar AluruAlexander BarsoukTermedia Publishing Housearticlelung cancer epidemiology incidence mortality trends survival aetiology risk factors.MedicineRENContemporary Oncology, Vol 25, Iss 1, Pp 45-52 (2021)
institution DOAJ
collection DOAJ
language EN
topic lung cancer
epidemiology
incidence
mortality
trends
survival
aetiology
risk factors.
Medicine
R
spellingShingle lung cancer
epidemiology
incidence
mortality
trends
survival
aetiology
risk factors.
Medicine
R
Krishna Chaitanya Thandra
Adam Barsouk
Kalyan Saginala
John Sukumar Aluru
Alexander Barsouk
Epidemiology of lung cancer
description Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the second most common cancer diagnosis in men and women (after prostate and breast cancer, respectively). With increasing access to tobacco and industrialization in developing nations, lung cancer incidence is rising globally. The average age of diagnosis is 70 years old. Men are twice as likely to be diagnosed with lung cancer, which largely reflects differences in tobacco consumption, although women may be more susceptible due to higher proportions of epidermal growth factor receptor mutations and the effects of oestrogen. African American men in the US are at the highest risk of lung cancer. Family history increases risk by 1.7-fold, with a greater risk among first-degree relatives. Tobacco smoking is the greatest preventable cause of death worldwide, accounting for up to 90% of lung cancer cases, and continued consumption is projected to increase global cancer incidence, particularly in developing nations such as China, Russia, and India. Second-hand smoke among children and spouses has likewise been implicated. Radon from natural underground uranium decay is the second leading cause of lung cancer in the developed world. Occupational hazards such as asbestos and environmental exposures such as air pollution, arsenic, and HIV and Tb infection have all been implicated in lung carcinogenesis, while cannabis smoking, electronic cigarettes, heated tobacco products, and COVID-19 have been hypothesized to increase risk.
format article
author Krishna Chaitanya Thandra
Adam Barsouk
Kalyan Saginala
John Sukumar Aluru
Alexander Barsouk
author_facet Krishna Chaitanya Thandra
Adam Barsouk
Kalyan Saginala
John Sukumar Aluru
Alexander Barsouk
author_sort Krishna Chaitanya Thandra
title Epidemiology of lung cancer
title_short Epidemiology of lung cancer
title_full Epidemiology of lung cancer
title_fullStr Epidemiology of lung cancer
title_full_unstemmed Epidemiology of lung cancer
title_sort epidemiology of lung cancer
publisher Termedia Publishing House
publishDate 2021
url https://doaj.org/article/5d63ebf684d04f7fbe13fb2f73b44c40
work_keys_str_mv AT krishnachaitanyathandra epidemiologyoflungcancer
AT adambarsouk epidemiologyoflungcancer
AT kalyansaginala epidemiologyoflungcancer
AT johnsukumaraluru epidemiologyoflungcancer
AT alexanderbarsouk epidemiologyoflungcancer
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