HSP70-mediated neuroprotection by combined treatment of valproic acid with hypothermia in a rat asphyxial cardiac arrest model.

It has been reported that valproic acid (VPA) combined with therapeutic hypothermia can improve survival and neurologic outcomes in a rat asphyxial cardiac arrest model. However, neuroprotective mechanisms of such combined treatment of valproic acid with hypothermia remains unclear. We hypothesized...

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Autores principales: Joo Suk Oh, Jungtaek Park, Kiwook Kim, Hyun Ho Jeong, Young Min Oh, Semin Choi, Kyoung Ho Choi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/5d67c9d20e2e4cb4bbac1be28907c2d8
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