Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia

The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the stu...

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Autores principales: O. V. Kalyuzhnaya, T. A. Bairova, V. V. Dolgikh, S. I. Kolesnikov
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Acceso en línea:https://doaj.org/article/5d78fba6b5db47cda2d898e34c7febd9
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spelling oai:doaj.org-article:5d78fba6b5db47cda2d898e34c7febd92021-11-23T06:14:31ZStudy of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia2541-94202587-9596https://doaj.org/article/5d78fba6b5db47cda2d898e34c7febd92014-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1822https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations.O. V. KalyuzhnayaT. A. BairovaV. V. DolgikhS. I. KolesnikovScientific Сentre for Family Health and Human Reproduction Problemsarticles1/s2apolipoprotein c3s1/s2allelegenotypeScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5, Pp 95-97 (2014)
institution DOAJ
collection DOAJ
language RU
topic s1/s2
apolipoprotein c3
s1/s2
allele
genotype
Science
Q
spellingShingle s1/s2
apolipoprotein c3
s1/s2
allele
genotype
Science
Q
O. V. Kalyuzhnaya
T. A. Bairova
V. V. Dolgikh
S. I. Kolesnikov
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
description The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations.
format article
author O. V. Kalyuzhnaya
T. A. Bairova
V. V. Dolgikh
S. I. Kolesnikov
author_facet O. V. Kalyuzhnaya
T. A. Bairova
V. V. Dolgikh
S. I. Kolesnikov
author_sort O. V. Kalyuzhnaya
title Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
title_short Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
title_full Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
title_fullStr Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
title_full_unstemmed Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
title_sort study of apolipoprotein c3 s1/s2 (c3238g, rs5128) polymorphism in caucasian population of eastern siberia
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2014
url https://doaj.org/article/5d78fba6b5db47cda2d898e34c7febd9
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AT vvdolgikh studyofapolipoproteinc3s1s2c3238grs5128polymorphismincaucasianpopulationofeasternsiberia
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