Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia
The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the stu...
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Scientific Сentre for Family Health and Human Reproduction Problems
2014
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oai:doaj.org-article:5d78fba6b5db47cda2d898e34c7febd92021-11-23T06:14:31ZStudy of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia2541-94202587-9596https://doaj.org/article/5d78fba6b5db47cda2d898e34c7febd92014-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1822https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations.O. V. KalyuzhnayaT. A. BairovaV. V. DolgikhS. I. KolesnikovScientific Сentre for Family Health and Human Reproduction Problemsarticles1/s2apolipoprotein c3s1/s2allelegenotypeScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5, Pp 95-97 (2014) |
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s1/s2 apolipoprotein c3 s1/s2 allele genotype Science Q |
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s1/s2 apolipoprotein c3 s1/s2 allele genotype Science Q O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
description |
The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations. |
format |
article |
author |
O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov |
author_facet |
O. V. Kalyuzhnaya T. A. Bairova V. V. Dolgikh S. I. Kolesnikov |
author_sort |
O. V. Kalyuzhnaya |
title |
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
title_short |
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
title_full |
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
title_fullStr |
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
title_full_unstemmed |
Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia |
title_sort |
study of apolipoprotein c3 s1/s2 (c3238g, rs5128) polymorphism in caucasian population of eastern siberia |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2014 |
url |
https://doaj.org/article/5d78fba6b5db47cda2d898e34c7febd9 |
work_keys_str_mv |
AT ovkalyuzhnaya studyofapolipoproteinc3s1s2c3238grs5128polymorphismincaucasianpopulationofeasternsiberia AT tabairova studyofapolipoproteinc3s1s2c3238grs5128polymorphismincaucasianpopulationofeasternsiberia AT vvdolgikh studyofapolipoproteinc3s1s2c3238grs5128polymorphismincaucasianpopulationofeasternsiberia AT sikolesnikov studyofapolipoproteinc3s1s2c3238grs5128polymorphismincaucasianpopulationofeasternsiberia |
_version_ |
1718417071365160960 |