Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection.
In addition to alpha1,3 glucan, mannan and mannan-linked proteins are expressed in the outer layer of Paracoccidioides brasiliensis yeasts. The recognition of mannosyl residues by multiple pathogen recognition receptors, such as the mannose receptor (MR), complement receptor 3 (CR3) and toll-like re...
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Main Authors: | , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Subjects: | |
Online Access: | https://doaj.org/article/5d79cf9d3d36463ba05e235cbf37805b |
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